Influenza Adaptations

Description

Virology (RNA Viruses) Flashcards on Influenza Adaptations, created by gina_evans0312 on 16/04/2014.
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Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 about 10 years ago
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Resource summary

Question Answer
1997- Locations East Asia, Africa and the EU
1997- Species Effected Lethal to birds and humans, still present in animal populations
1997- Spread No sustained person-person spread, instead picked up from birds
1997- Genome NA & HA From aquatic wild virus, poultry & wild birds
1997- Changes Resistant to HA, sensitive to NA inhibitors
2009 (H1N1)- Source Mexico, rapid spread
2009 (H1N1)- Cause of Increased Death Rate Altered receptor causing infection deep in the lungs
2012 (H7N9)- HA Alterations Leads to increased salic acid binding
2012 (H7N9)- Transmission Better aerosol transmission
2012 (H7N9)- NA Mutation Leads to increased replication in the respiratory tract
2012 (H7N9)- PB2 Allows increased adaptation in mammals
2012 (H7N9)- Changes HA inhibitor resistant, NA inhibitor sensitive
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