762814
Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
about 10 years ago
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| Question | Answer |
| Making HIV mRNA | Entire genome is transcribed as single mRNA, with '5 promoter and 3' polyA tail |
| Gene Splicing | Used to make the necessary proteins |
| Proteases | Placed inside the virions to mature them after budding |
| 'Tat' Gene- Role | Aids transcription of genome, by aiding in poly-phosphorylation of RNA polymerase |
| 'Tat' Gene- Binding | Binds to stem-loop structure at the 5' end of the integrated genome |
| 'Tat' Gene- Co Proteins | Causes CDK9 & cyclin to also bind, which poly-P RNA polymerase |
| 'Vif' Gene- Role | Aids cell survival through targeted degredation of APOBEC, a cell survival protein |
| 'Tat' Gene- Origin | Spliced protein |
| APOBEC (Cell Protein) - Role | Enters virion and causes C->U conversion during reverse transcription |
| 'Rev' Gene- Role | Aids export of viral RNA from nucleus to cytoplasm (using RRE region) |
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