Human health and physiology - Antibodies and AIDS

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Biology (Human Health and Physiology) Mind Map on Human health and physiology - Antibodies and AIDS, created by leonie1997 on 04/18/2014.
leonie1997
Mind Map by leonie1997, updated more than 1 year ago
leonie1997
Created by leonie1997 about 11 years ago
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Resource summary

Human health and physiology - Antibodies and AIDS
  1. Production of antibodies
    1. 1. Antibodies are made by lymphocytes, one of the two main types of leukocyte.
      1. 2. A lymphocyte can only make one type of antibody so a huge number of different lymphocyte types are needed. Each lymphocyte puts some of the antibody that it can make into its plasma membrane with the antigen-combining site projecting outwards.
        1. 3. When a pathogen enters the body, its antigen binds to the antibodies in the plasma membrane of one type of lymphocyte.
          1. 4. When the antigen binds to the antibodies on the surface of a lymphocyte, this lymphocyte becomes active and divides by mitosis to produce a clone of many identical cells.
            1. 5. The clone of cells starts to produce large quantities of the same antibody - the antibody needed to defend the body against the pathogen.
            2. AIDS - a syndrome caused by a vius
              1. AIDS shows how vital the bodies defenses against disease are.
                1. Destruction of the immune system lead inevitably to death.
                2. AIDS is an example of a syndrome.
                  1. A syndrome is a group of symptoms that are found together. Individuals with AIDS have low numbers of one type of lymphocyte together with weight loss and a variety of diseases cause by viruses, bacteria, fungi and protozoa. These diseases weaken the body and eventually cause death.
                  2. Cause:
                    1. HIV causes AIDS
                      1. The virus infects a type of lymphocyte that plays a vital role in antibody production.
                        1. Over a period of years these lymphocytes are destroyed and antibodies cannot be produced.
                          1. Without a functioning immune system, the body is vulnerable to pathogens that would normally be controlled easily.
                          2. Transmission
                            1. HIV does not survive for long outside of the body and cannot easily pass through the skin.
                              1. Transmission involves the transfer of bodily fluids from on an infected person to an uninfected one.
                                1. Through small cuts or tears in the vagina, penis, mouth or intestine during vaginal, anal or oral sex.
                                  1. In traces of blood on a hypodermic needle that is shared by intravenous drug abusers.
                                    1. Across the placenta from mother to baby, or through cuts during childbirth or in milk during breast-feeding.
                                      1. In transfused blood or with blood products such as Factor VIII used to treat hemophiliacs.
                                      2. Social Implications
                                        1. Family and friends suffer grief.
                                          1. Families become poorer if the individual with AIDS was the wage earner and is refused life insurance.
                                            1. Individuals infected with HIV may become stigmatized and not find partners, housing or employment.
                                              1. Sexual activity in a population may be reduced because of the fear of AIDS.
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