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Spinal muscular atrophy - Peripheral neuropathies

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Neurology Mind Map on Spinal muscular atrophy - Peripheral neuropathies, created by LewisLewis on 05/11/2014.
LewisLewis
Mind Map by LewisLewis, updated more than 1 year ago
LewisLewis
Created by LewisLewis almost 11 years ago
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Resource summary

Spinal muscular atrophy - Peripheral neuropathies
  1. Peripheral neuropathies
    1. Causes
      1. Nerve fiber
        1. Dysfunction of the motor or sensory cell
          1. Problem regarding protein synthesis
            1. Trauma
              1. Axon distal to trauma point will degenerate in 7 days
            2. Myelin sheath
            3. Types
              1. Clinical classification
                1. Type of distribution of the damage
                  1. Multineuropathy
                    1. Mononeuropathy
                      1. Polyneuropathy
                      2. Types of fibers affected
                        1. Sensitive neuropathies
                          1. Motor neuropathies
                            1. Sensory-motor neuropathies
                              1. Autonomic neuropathies
                              2. Type of presentation
                                1. Acute neuropathies
                                  1. Chronic/insidious onset neuropathies
                                    1. Sub-acute
                                  2. Etiology
                                    1. Genetic neuropathies
                                      1. Axonal
                                        1. Demyelinating
                                        2. Acquired neuropathies
                                          1. Metabolic
                                            1. Diabetes is the first cause of peripheral neuropathy
                                            2. Deficiency
                                              1. Toxic
                                                1. Infections
                                                  1. Immune mediated
                                                    1. Vascular
                                                      1. Mechanic
                                                    2. Clinical characteristics
                                                      1. Symptoms
                                                        1. Motor
                                                          1. Sensitive
                                                            1. Neurovegetative
                                                            2. Signs
                                                              1. Motor
                                                                1. Sensitive
                                                                2. Enter text here
                                                                3. Diagnosis
                                                                  1. Blood tests
                                                                    1. CSF
                                                                      1. EMG and ENG
                                                                        1. Motor and sensory conduction studies
                                                                        2. Nerve biopsy
                                                                        3. Dysimmune neuropathies
                                                                          1. Demyelinating neuropathies
                                                                            1. Axonal neuropathies
                                                                            2. Guillain-Barré syndrome
                                                                              1. Onset
                                                                                1. Pain
                                                                                  1. Paresthesia
                                                                                    1. Weakness
                                                                                      1. Respiratory failure
                                                                                        1. Cranial nerves involvement
                                                                                          1. Deep tendon reflexes
                                                                                            1. Autonomic dysfucntions
                                                                                            2. Progression
                                                                                              1. Death
                                                                                                1. Prodrome phase
                                                                                                  1. Treatment
                                                                                                    1. Steroids generally not administered
                                                                                                      1. Remove antibodies as quickly as possible
                                                                                                        1. Plasmapheresis
                                                                                                          1. infuse high levels of immunoglobulins derived from different donors
                                                                                                    2. Spinal muscular atrophy
                                                                                                      1. mutations in
                                                                                                        1. SMN1
                                                                                                          1. SMN2
                                                                                                          2. Types
                                                                                                            1. Werding-Hoffmann
                                                                                                              1. Intermediate form
                                                                                                                1. Kugelberg-Welander syndrome
                                                                                                                  1. Adult form
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