Flashcards
schizophrenia - biological explanations
Flashcards do conjunto (25)
- 1what do you call genes that are linked to diseasecandidate genes
- 2who came up with the genetic basis for schzGottesman
genetic basis - 3the closer you are related....the more at risk you are of getting schz
- 4identical twins share what % of genes and what % risk os schz100
48 - 5non identical twins share what % of genes and what % risk os schz50
17 - 6siblings share what % of genes and what % risk os schz50
9 - 7grand children share what % of genes and what % risk os schz25
5 - 8general population share what % of genes and what % risk os schzN/A
1 - 9candidate genes arepolygenic
they affect neurotransmitters - 10who did the study for candidate genesRiphe
- 11how many patients and controls did Riphe have for the candidate genes studypatients - 37,000
controls - 113,000 - 12how many separate genes did Riphe find are liked to schz108
- 13what is the dopamine hypothesismade up of
neurotransmitters
hyperdopaminergia in sub cortex
in the cortex - 14what are neurotransmitterschemical messengers
- 15how is dopamine linked to schzit is a neurotransmitter that has an excitatory effect - high levels associated with schz
- 16what is the hyperdopaminergia in the sub cortexlooks at roles of high levels of dopamine
e.g. too much in Broca's area is linked with speech poverty - 17in the cortexlow levels of dopamine linked to negative symptoms
- 18what are neural correlatesmeasures of structure and function of the brain
- 19who looked at neural correlates in negative symptomsJuckel
- 20abnormality where causes avolition (negative symptom)ventral striatum
low activity - 21who looked at neural correlates in positive symptomsAllen
- 22abnormality where causes positive symptomssuperior temporal
low activity - 23evaluation biological explanations - evidence for genetic susceptibility for and againstGottesman
risk of schz increases when closely related
Tienari
adoption still has high rates of schz if parents have it - 24evaluation biological explanations - mixed evidence dopamine hypothesisdopamine agonists (e.g. amphetamines) increase dopamine so more likely to get schz
dopamine antipsychotics decrease dopamine so reduces schz
Riphe - other neurotransmitters also effect (glutamate) - 25evaluation biological explanations - what about cause and effectcause and effect does affect all of the studies (which one first)
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- AS - Level psychology (A2 chapter 8 - Schizophrenia ) FlashCards sobre schizophrenia - biological explanations , criado por Daisy U em 05-01-2017.
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- Daisy U
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