Mapa mental
TCA Cycle
Mind map: TCA cycle
Conteúdo do mapa
TCA Cycle
Pyruvate
- Acetyl-CoA
- Citrate
- cis-Aconitate
- Isocitrate
- alpha-ketoglutarate
- Succinyl-CoA
- Succinate
- Fumarate
- Malate
- OAA
- Aspartate & Asparagine
- Pyrimidines
- Phosphoenolpyruvate (PEP)
- Glucose
- Ser, Gly, Cys, Phe, Tyr, Trp
- Aspartate & Asparagine
- Generated also by malic enzyme
- OAA
- Malate
- FADH2
- Fumarate
- Porphyrins, heme
- GTP/ATP
- Self-inhibiting/inhibits Acetyl-CoA formation
- Gain of symmetry; cannot distinguish original acetyl
- Succinate
- Glutamate
- Purines
- Arginine, Proline, Glutamine
- Succinyl-CoA
- NADH
- Inhibits
- NAD+ & Mn2+ required
- alpha-ketoglutarate
- Stereospecific; asymmetric binding
- Isocitrate
- Fatty acids and sterols
- Inhibit
- Condensation reaction
- cis-Aconitate
- Citrate
- Total cycle is doubled because there are 2 pyruvate
- Pyruvate dehydrogenase complex
- Coenzymes
- TPP
- Lipoate
- NAD+
- FAD
- Substrate channeling
- Coenzymes
- Acetyl-CoA
Regulation
- ATP inhibits
- ADP/AMP & Pi activate
- Ca ions activate
Enzymatic processes involved
- Dehydration/hydration
- Transamination
- Pyruvate dehydrogenase complex
- Substrate level phosphorylation
- Electron-carrier generators/redox
- Oxidative decarboxylation
- Removes CO2 irreversibly, usually taking a carboxyl
- Dehydrogenation
- Oxidative decarboxylation
Informações
- Descrição
- The main flow of the Citric Acid/Krebs/Tri-Carboxylic Acid cycle.
- Criado por
- Keenan Flynn
- Visualizações
- 109
- Tags
- Avaliação