Flashcards
Viral Hepatitis (A, B, C, D, E)
Flashcards do conjunto (11)
- 1Hepatitis A Virus Structure? (2) Transmission? (3) Immunity? (3)STRUCTURE:
Picornavirus; ssRNA
TRANSMISSION:
Faeco-oral; contaminated food/water; person-person
IMMUNITY:
After previous infection; after vaccine; after hep A immunoglobulin - 2Hepatitis A Incubation period? (1) Symptoms? (6) Prognosis? (3) Treatment? (2)INCUBATION PERIOD:
30 days
SYMPTOMS:
Fever; abdominal pain; diarrhoea; jaundice; itch; muscle pains
PROGNOSIS:
Rarely fatal; self-limiting; more severe with increasing age
TREATMENT:
Maintain hydration; avoid alcohol - 3Diagnosis of Hepatitis A Serology? (2) Other tests? (2)SEROLOGY:
Hepatitis A IgM Positive - indicates new infection
IgG Positive - indicates previous infection/vaccination
OTHER TESTS:
LFTs - abnormal, e.g. elevated AST/ALT
RNA in stool - indicates new infection - 4Hepatitis A Vaccine Efficacy? (1) Duration of protection? (1) Pre-exposure use? (4) Post-exposure use? (2)EFFICACY: 95%
PROTECTION: life
PRE-EXPOSURE USE:
Travellers; homosexual men; IVDUs; chronic liver disease patients
POST-EXPOSURE USE:
Outbreak control (effective up to 7 days after) - 5Hepatitis A Immunoglobin Duration of protection? (1) Pre-exposure use? (2) Post-exposure use? (2)PROTECTION: 3-6 months
PRE-EXPOSURE USE:
Patients allergic to vaccine; travellers with less than 4 weeks before travel
POST-EXPOSURE USE:
Outbreak control (effective up to 14 days after) - 6Chronic carriage of Hepatitis A (1)Not possible
- 7Hepatitis E Virus Structure? (2) Transmission? (2) Immunity? (1)STRUCTURE:
ssRNA; calicivirus
TRANSMISSION:
Faeco-oral; infected meat
IMMUNITY:
None - 8Hepatitis E Incubation period? (1) Symptoms? (7) Prognosis? (2) Treatment? (3)INCUBATION PERIOD:
40 days
SYMPTOMS:
Fever; abdominal pain; diarrhoea; jaundice; itch; muscle pain; neurological effects
PROGNOSIS:
More fatal than hep A; fatality rate: 1-3%
TREATMENT:
Supportive, e.g. maintain hydration, avoid alcohol - 9Diagnosis of Hepatitis E Serology? (1) Other tests? (1)SEROLOGY:
Hep E IgM Positive - indicates new infection
OTHER TESTS:
Hep E Virus in stool - indicates new infection - 10Hepatitis E Vaccine (1)None
- 11Chronic carriage of hepatitis E (2)Yes
WHO?
Highly immunosuppressed patients
Informações
- Descrição
- Transmission, clinical features, diagnosis, vaccinations and treatment of viral hepatitis (A, B, C, D, E) Week 3; See VIRAL HEPATITIS LECTURE
- Criado por
- Melissa Denker
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- 56
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