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Quiz

Endocrine Block - THYROID (Week 3)

Melissa Denker 10 questions

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Questions in this quiz (10)

  1. 1Which connection allows communication between the hypothalamus and anterior pituitary gland?
    1. AHypophyseal portal system
    2. BHypothalamic hypophyseal tract
    3. CInfundibulum
    4. DSphenoid sinus cavity surrounding the pituitary gland
  2. 2Which connection allows communication between the hypothalamus and the posterior pituitary gland?
    1. AHypophyseal portal system
    2. BHypothalamic hypophyseal tract
    3. CInfundibulum
    4. DSphenoid sinus cavity surrounding the pituitary gland
  3. 3Which hormones are produced by the posterior pituitary gland?
    1. AOxytocin
    2. BADH
    3. CProlactin
    4. DTSH
    5. EFSH/LH
    6. FGH
    7. GACTH
  4. 4What is the correct order of the following anterior pituitary cell types, from most abundant to least abundant?
    1. ASomatotrophs (50%)
      Lactotrophs (20%)
      Corticotrophs (10-15%)
      Gonadotrophs (10%)
      Thyrotrophs (5%)
    2. BSomatotrophs (50%)
      Lactotrophs (20%)
      Gonadotrophs (10-15%)
      Corticotrophs (10%)
      Thyrotrophs (5%)
    3. CGonadotrophs (50%)
      Lactotrophs (20%)
      Corticotrophs (10-15%)
      Thyrotrophs (10%)
      Somatotrophs (5%)
    4. DSomatotrophs (50%)
      Lactotrophs (20%)
      Corticotrophs (10-15%)
      Thyrotrophs (10%)
      Gonadotrophs (5%)
    5. ECorticotrophs (50%)
      Lactotrophs (20%)
      Somatotrophs (10-15%)
      Gonadotrophs (10%)
      Thyrotrophs (5%)
  5. 5What are the 6 hormones released by the anterior pituitary gland?
    1. AADH
    2. BOxytocin
    3. CGH
    4. DFSH/LH
    5. EProlactin
    6. FACTH
    7. GTSH
  6. 6Which hypothalamic hormone stimulates the secretion of adrenocorticotrophic hormone (ACTH) from the anterior pituitary gland?
    1. ACorticotrophic releasing hormone (CRH)
    2. BThyroid releasing hormone (TRH)
    3. CGrowth hormone releasing hormone (GHRH)
    4. DGonadotrophin releasing hormone (GnRH)
    5. EDopamine
  7. 7Which test results would indicate cranial diabetes insipidus?
    1. AWater deprivation test - patients are desperate to drink; urine osmolality remains low
      Response to ADH - DI improves
    2. BWater deprivation test - patients are desperate to drink; urine osmolality stays low
      Response to ADH - DI does not improve
    3. CWater deprivation test - urine osmolality becomes high (i.e. concentrated)
      Response to ADH - DI improves
    4. DWater deprivation test - urine osmolality becomes high (i.e. becomes concentrated)
      Response to ADH - DI does not improve
  8. 8What is the correct order for rates of functional pituitary adenomas?
    1. AProlactinomas (30%)
      Cushing's disease (20%)
      Acromegaly (15%)
      TSHoma (<1%)
    2. BProlactinomas (30%)
      Cushing's disease (20%)
      TSHomas (15%)
      Acromegaly (<1%)
    3. CAcromegaly (30%)
      Cushing's disease (20%)
      Prolactinomas (15%)
      TSHoma (<1%)
    4. DProlactinomas (30%)
      TSHoma (20%)
      Acromegaly (15%)
      Cushing's disease (<1%)
  9. 9Describe the process of thyroid hormone production:
    1. Iodine is actively transported into the [blank_start]follicular thyroid cells[blank_end] via [blank_start]sodium iodide transporters[blank_end] on the basolateral side of the cell (this is called [blank_start]iodide trapping[blank_end])
    2. Iodine diffuses to the luminal side of the cell
    3. Iodine is transported into the follicle lumen by [blank_start]pendrin[blank_end], a membrane transporter
    4. The follicle cells secrete [blank_start]thyroglobulin[blank_end] (containing ~70 [blank_start]tyrosine[blank_end] amino acids) into the lumen
    5. Iodide ions undergo [blank_start]oxidation[blank_end] to form [blank_start]iodine[blank_end] via the action of the enzyme [blank_start]hydrogen peroxidase[blank_end]
    6. [blank_start]Organification[blank_end] of the thyroglobulin molecule:
    ---Iodine binds to tyrosine amino acids within the thyroglobulin molecule via the action of [blank_start]thyroid peroxidase[blank_end]
    ---This forms [blank_start]monoiodotyrosine[blank_end]
    ---This undergoes further iodine binding to form [blank_start]diiodotyrosine[blank_end]
    ---MIT/DIT molecules are coupled to each other
    7. If two DIT molecules couple together, [blank_start]T4 (thyroxine)[blank_end] is formed
    8. If one MIT molecule couples with one DIT molecule, [blank_start]T3 (triiodothyronine)[blank_end] is formed
    1. Afollicular thyroid cells
    2. Bsodium iodide transporters
    3. Ciodide trapping
    4. Dpendrin
    5. Ethyroglobulin
    6. Ftyrosine
    7. Goxidation
    8. Hiodine
    9. Ihydrogen peroxidase
    10. JOrganification
    11. Ktyrosine peroxidase
    12. Lmonoiodotyrosine (MIT)
    13. Mdiiodotyrosine (DIT)
    14. NT4 (thyroxine)
    15. OT3 (triiodothyronine)
  10. 10How much more concentrated is iodine in the thyroid than in the blood?
    1. Ax30
    2. Bx60
    3. Cx90
    4. Dx120

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Description
Undergraduate MBChB Year 2 Quiz on Endocrine Block - THYROID (Week 3), created by Melissa Denker on 30/11/2015.
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