Karteikarten
Motor Proteins- Cytoplasmic Dyenin
Karten in diesem Stapel (22)
- 1Size of Cytoplasmic Dyenin350 kDa
- 2Dyenin SuperfamilyAAA+
- 3Direction of C.Dyenin movementFrom plus end to minus end
- 4CargomRNA, proteins, viruses- it varies
- 5Role of Multiple Light ChainWhere cargo binds
- 6No of heavy chains2
- 7AAA+ domainsForm a hexameric motor domain
- 8Role of Linker domainDimerises protein
- 9Coiled coilLinks AAA+ motor heads to microtubule binding site
- 10N-terminusLight chains, dimerisation and cargo binding
- 11C terminusAAA+ motors, tubulin binding and linking coiled coil stalk
- 12Location of ATP bindingAAA+ domains
- 13Binding of ATP changesRelative positions of linker domains and coiled coil
- 14ATP binding causes _ of MTBDWeakening of MTBD to tubulin
- 15No of ATP req'dUnclear
- 16Distance moved by Dyenin heads16nm- but it varies a lot
- 17Largest known 'step' of head30 nm
- 18Backwards movementPossible
- 19Movement onto other microtubulesAllows it to pass kinesin (kinesin can't change M.T's)
- 20Mutant with non-functioning ATP headStill moved, but slowly and with no powerstroke
- 21Co-ordination of Dyenin movementMuch less co-ordinated than kinesin
- 22Mechanism of movementHand over Hand model
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- Beschreibung
- Structural Basis for Biological Function (Molecular Motors) Karteikarten am Motor Proteins- Cytoplasmic Dyenin, erstellt von gina_evans0312 am 15/12/2013.
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- gina_evans0312
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