Interstitial Lung Disease (reduced compliance, diffusion capacity and lung volume)

Beschreibung

Pathology Mindmap am Interstitial Lung Disease (reduced compliance, diffusion capacity and lung volume), erstellt von Emma Jones am 07/09/2013.
Emma Jones
Mindmap von Emma Jones, aktualisiert more than 1 year ago
Emma Jones
Erstellt von Emma Jones vor mehr als 10 Jahre
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Zusammenfassung der Ressource

Interstitial Lung Disease (reduced compliance, diffusion capacity and lung volume)
  1. Fibrosing
    1. UIP: Usual: unknown cause, temporally heterogeneous, honeycomb lung, expanded alveolar septa
      1. NSIP: Non-specific: idiopathic, temporally homogeneous
        1. COP: Cryptogenic organising pneumonia
          1. Autoimmune related: RA, SLE
            1. Pneumoconiosis: inhaled dusts: anthracosis, silicosis, asbetosis
              1. Asbestosis: thick collagen layer on lung parenchyma, may calcify
            2. Acute interstitial lung disease
              1. ARDS: Acute Respiratory Distress Syndrome / DAD: Diffuse alveolar damage
                1. MACRO: red heavy lungs
                  1. MICRO:
                    1. Oedema in alveolar walls
                      1. Hyaline membranes: fibrin + epithelial cell debris
                        1. Type II pneumocytes proliferate & differentiate to type I
                        2. Causes
                          1. Trauma, infection, shock, gastric aspiration, gas inhalation, DIC
                        3. Respiratory distress in the newborn = ARDS in newborn
                          1. Birthweight <2.5kg, <36wks gestation, maternal diabetes, caesarean
                            1. Insufficient surfactant
                              1. Alveoli collapse, hypoxia
                                1. Cell damage, oedema, fibrin
                                  1. Hyaline membrane
                            2. Acute interstitial pneumonia = ARDS without known cause
                            3. Sarcoidosis
                              1. Systemic disease, disseminated well-formed granulomas
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