BLOOD-BORNE VIRUSES - created from Mind Map

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Human Immunodeficiency virus (HIV) / Lentivirus

Hepatitis B

Hepatitis C virus

Family: Retroviridae

Roughly spherical

Enveloped

Icosahedral capsid

2 copies (+) Single-stranded RNA (ssRNA)

120nm

Upon entry into the target cell, the viral RNA genome is converted (reverse transcribed) into double-stranded DNA by a virally encoded reverse transcriptase that is transported along with the viral genome in the virus particle

The resulting viral DNA is then imported into the cell nucleus and integrated into the cellular DNA by a virally encoded integrase and host co-factors.

Dane particle (virion)

Family: Hepadnaviridae

Enveloped

Icosahedral capsid

Double-stranded DNA (dsDNA)

42nm

Family: Flaviviridae

Enveloped

Icosahedral capsid

(+) Single-stranded RNA (ssRNA)

55-65nm