451493
Beschreibung
Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor mehr als 10 Jahre
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Frage 1
Frage
What is the main problem of protein translocation?
Antworten
-
Hydrophillic proteins must transverse two hydrophobic membranes and a hydrophillic space
-
Proteins must be unfolded and refolded again
-
Proteins must pass through an extremely crowded cytoplasm
Frage 2
Frage
Proteins to be secreted directly after translation have a peptidase sequence at the C-terminus
Antworten
- True
- False
Frage 3
Frage
Which of the following parts of the peptidase sequence are closest to the N-terminus?
Antworten
-
The basic residues
-
The hydrophobic region
-
Peptidase cleavage recognition site
Frage 4
Frage
There are 1-2 basic residues in the signal sequence, but the hydrophobic sequence is variable in length
Antworten
- True
- False
Frage 5
Frage
When a protein is transcribed with the Peptidase signal site, what protein binds to its hydrophobic region?
Antworten
-
Signal Recognition Protein
-
Ftsy- a GTPase
-
SecYEG- a bacterial pore
Frage 6
Frage
Ftsy transfers the protein into the pore
Antworten
- True
- False
Frage 7
Frage
Which of the following provide the driving force for protein translocation across the membrane
Antworten
-
Protonmotive force
-
FtsY's GTPase
-
Protein translation
Frage 8
Frage
What binds to the nascent polypeptide if Post-Translational Translocation takes place?
Antworten
-
SecB
-
SecA
-
SecC
Frage 9
Frage
Post-Translational Translocation sequences have a string of hydrophobic amino acids, same as in Translational Translocation
Antworten
- True
- False
Frage 10
Frage
What is the role of Sec_ ?
Antworten
-
To keep the protein in solution till it binds to SecA at the pore
-
To fold the protein on its way to the periplasmic more
-
To stop the protein folding on its way to SecC
Frage 11
Frage
What forces are required to get a Post-Translational Translocation through the pore?
Antworten
-
GTPase of FtsY
-
ATP hydrolysis by SecB
-
Protonmotive Force
Frage 12
Frage
Once inside the required membrane, what protein removes the peptide sequence?
Antworten
-
Signal peptidase
-
Signal lyase
-
Signal Isomerase
Frage 13
Frage
The protein only folds after the signal sequence is cleaved
Antworten
- True
- False
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