Quiz
Microbiology MCQs 3rd Year Final- PMU
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Questions in this quiz (152)
1The reaction of antibody with a non soluble antigen or an antigen-cated particles result in formation of visible to the eye clumb is called
- Aagglutination
- Bprecipitation
- Cneutralization
- Dcomplement fixation test
2ELlSA makes use of:
- Afluorenlubels
- Benzyme
- Cradioactive lubels
- DIt is not a labeled immune for...
3widal from used to.....
- Aslide agglutination test
- Btube agglutination
- CCUT
- Dlectin pathway
4Which of the following immunoglobulins may be transferes to the fetus during pregnancy
- AlgG
- BlgM
5The genus specific name for group A streptococci is
- Astreptococcus pneumonia
- Bstreptococcus viridans
- Cstreptococcus diphtheria
- Dstreptococcus pyogenes
6The main pathogenic factor of corynebacterium diphtheria is
- Aan endotoxin
- Ban exotoxin
- Ca spore
- Da protein
7The specific prophylaxis of diphtheria is performed by
- Aa toxoid
- Ba killed vaccine
- Cpassive transfer at serum
- Da live vaccine
8Which of the following statement concerning cholera infection is correct?
- Adeath occurs in 46 weeks exclusion and respiratory failure
- Bthe disease is marked by microorganism invasion and hemorrhage of large intestine
- Cvibrio cholera produce an acute fehrile disease with
- Dthe disease is rapidly progressive and maybe fatal in 2 days because of bacterial multiplication in the gut and shock
9Beta lactamase production is a major problem for treatment of infections caused by:
- ACorynebacterium diphtheria
- BNeisseria meningitides
- CStaphylococcus aureus
- DTreponemapallidum
10HIV has been shown to be transmitted by one of the following except
- ASexual contact
- BPerinatal infection
- CMosquitos
- DBlood transfer
11Each organism is identified by two names including:
- Afamily and kingdom
- Bgenus and species
- Cfamily and species
- Dfamily and genus
12[blank_start]Simple[blank_end] techniques of staining make use of only one dye,where as [blank_start]Complex[blank_end] staining a combination of dyes?
- ASimple
- BComplex
13The volutine granules of corynebacterium diptheria are visualized by [blank_start]Neisser[blank_end] Staining
- ANeisser
14The following structure are located in the cytoplasmic membrane?
- Aspore
- Bnucleotid
- Cribosomes
- Dcapsule
15Based on their cell wall structure bacteria are divided into:
- Agram(+) and gram(-)
- Baerobe and anerobe
- Csphere and spinal
- Dcocci and rods
16Peptidoglycan polymers are found only in:
- Abacterial cell
- Banimal cell
- Ca,b
- Dviruses
17Flagella are present in every bacterium
- ATrue
- BFalse
18Sporulation appears to be
- Aan initiation of the bacterium cell
- Ba reaction to conditions that are unfavorable for normal growth
- Ca status to resist desiccation and other harmful conditions
- Da,b
- Eb,c
19The complete killing or removal of all microorganisms including bacterial spores is called?
- Asterilization
- Bdisinfection
- Cantisepsis
- Dnon is true
20Cytoplasm contains:
- Astorage granules
- Bspores
- Ccapsules
21Which of following component are not found in the gram negative cell wall?
- Aamino acids
- Blipopolysaccharides
- Cpeptidoglycan
- Dteichoic acids
22Pfeiffer technique of staining makes use of following dye?
- Amethylene blue
- Bziehl’s fuchsine
- Cneutral red
- Dgentian violet
23Which of the following structure contains genes for enzymes and antibiotic resistance
- Aplasmld
- Bpilli
- Ccapsules
- Dplasma membrane
24Which of the following is the most important structure related to microbial attachment to cells
- Aflagella
- Bplasmid
- Cpeptidoglycan
- Dglycocalix
25Which of the following is not a gram negative microbe
- AClostridum perfringes
- BVibrio cholerae
- Cexcheriehia
- Dbordetella
26What causes it to be pink
- Apheiffer's fuchsine
- Bgram iodine
- Ccrystale violet
- Dneisser
27Selective media are designed to
- Asupport the growth of the desires microorganisms
- Binhibit the growth of non-desired microorganisms
- Ca+b
- Dnone of the above
28Which part of the antibody molecule reacts with the antigenic determinant agent
- Athe fab fragment
- Bthe fe fragment
- Cthe constant H region
- Dthe constants
29The chemical complement pathway is activated by
- Amicrobial endotoxins
- Bantigen-antibody complex
- Cmicrobial proteins
30All of the following statement about exotoxins are true expect
- Athey are produce mainly by gram (+) bacteria
- Bthey may be neutralized by antitoxins
- Cthey are proteins
- Dthey are heat stable at 100*
31In Solid media bacterial growth is detected by observing
- Aappearance of colonies
- Bdevelopment of pellet
- Cdevelopment of turbidity
- Da surface membrane
32The last phase of bacterial growth curve is:
- Alog phase
- Blag phase
- Cstationary phase
- Dphase of decline
33Which of the following component is not found in the gram(-) cell wall
- Alipopolysaccharide
- Bpeptidoglycan
- Cteichoic acids
- DO antigen
34The antiseptic is:
- Aan antimicrobial agent that can be used on inanimate object
- Ban antimicrobial agent that can be used on living tissue
- Can antibiotic
- Dan enzyme
35Klett is a staining procedure for visualizing:
- Aspores
- Bcapsules
- Cvolutine granules
- Dnucleotid
36All of the following media are differential except:
- ATeilurite agar
- BEosin-methylene blue agar(Levine)
- CMoller-hiton agar
- DDeoxycholate citrate
37Immunoprophylaxis of tuberculosis includes:
- Alive affenuated vaccine BCG
- Binjection of antimycobacterial serum
- Cpassive transfer of ready made antibodies from sensitized person
- Da toxoid
38Passive immunization is an application of:
- Asmall doses of infective agent
- Bready made antibodies, formed by another host in response to artificial immunization or to natural infection
- Ctoxoids
- Dkilled vaccines
39Which of the following statements about exotoxins are true:
- Athey are produced mainly by gram(+) bacteria
- Bthey may be neutralized by antitoxins
- Cthey are proteins
- Dthey are heat stable at 100*
40Which of the following is not a distinctive characteristic of viruses
- Aviruses lack the machinery for protein synthesis
- Bviruses require living cells for replication
- Cviruses replicate by a process of binary fission
- Dviral genomes are either DNA or RNA but not both
41the immune response elicited by Salk’s inactivated polio vaccine is deficient in specific
- Asecretory lgA
- Bserum IgA
- Cserum lgM
- DIgG
42All of the following are characteristics of the human immunodeficiency virus(HIV)expect?
- Ait bind to CD4 molecule preferentially
- Bit contains gp120 and gp30 envelope proteins
- Cit is the causative agent of AIDS
- Dit contains DNA within its core
43Complement fixation test requires
- Adissolved antigen
- Bcorpusculum antigen
- Cantitoxin
- Dcomplement
44Which of the immunoglobin molecule is pentamenie
- AlgM
- BIgG
- ClgD
- DlgE
- ElgA
45Resection of the transplanted organ due to preformed antibodies in recipient is defined
- Ahyper acute
- Baclerated
- Cacute
- Dchronic
46microorganisms can be defined as living creatures so small that are not visible by eye
- ATrue
- BFalse
47Loffler staining procedure stains bacteria in
- Ablue
- Bred
- Cgreen
- Dyellow
48Which of the following is not true related to endotoxins
- Aare secreted from cells
- Bcan be linked to meningococcemia
- Cproduced by gram negative microorganism
- Dcan cause fever
49Gram negative bacteria differ from gram(+) organism because they passes?
- ALPC(A)
- BPeptidoglycan
- COnly a cytoplasmic membrane
- DLipoteichoic acid
50Most bacteria increase in number through the process of
- Abinary fission
- Bbudding
- Csporulation
- Dsexual reproduction
51The term “growth” when for microorganism refer to
- Aincrease in cell number
- Bproduction of endospores
- Cthe age and size of the cell
- Dall of the above
52All of the following statement about bacteria cell division are true except:
- Aall bacteria double their number every 1 hour
- Bbacterial times are influenced by environmental conditions
- Cthe two bacterial cells following division are genetically identical, they are ones
- Dall the above
53Bacterial nucleotid consist of
- Ano chromosomes
- Bone chromosome
- Cseveral chromosome
54Bacterial capsule can be visual sated by:
- Agram stain
- Bloeffler stain
- Cklett stain
- Dmoller stain
55Lipopolysacharides can be found in large amount in:
- Agram(+) bacterial wall
- Bgram (-) bacterial wall
- Cboth
- Dnone of above
56Complex methods for bacterial staining are
- ALoeffler stain
- BPfefiffer stain
- CGram stain
- DZiehI-Neelsen stain
57Specific identity (serotype) of influenza virus can be accomplished by:
- Ahemmagglutination inhibition test
- Bneutralization test
- Ccomplement fixation test
- Dhemadsorbtion test
58enlargement of one or both parotid glands in the common clinical manifestation of:
- Ameasles
- Bmumps
- Crubella
- Dgrippe
59The initial replication of human poliovirus starts in:
- Apharyngeal and intestinal mucosa
- Bblood
- Cbrain
- Djoint
60In congenital rubella the fetus produce:
- AIgM
- BIgG
- ClgA
- DlgE
61The most common classification system used in microbiology is binomal and was established by:
- APasteur
- BKoch
- CLinnaeus
- DGram
62Common pili play role in bacterial;
- Aconjugation
- Badherence to surface
- Cmotility
- Dprecipitation
63Endotoxins are:
- Afound in gram (+) bacteria
- Bfound in gram(-) bacteria
- Cproteins
- Da structural component of the spore
64Which of the following techniques allows to start with a single piece of microbial DNA and produce billions of copies in matter of hour
- APCR
- BELlSA
- Chybridoma biotechnology
- DIFA
65Which of the following is the fastest way to kill endospores
- Aautoclave at 121*C
- Bhot air at 160*C
- Cclorox solution
- Dfiltration
66Gram positive bacterium is most susceptible to the action of penicillin in the following phase of growth?
- Alag
- Blog
- Cstationary
- Ddecline
67The primary immune response include participation of?
- AIgM
- BlgG
- ClgD
- DlgE
- ElgA
68The first vaccine was used against:
- Ameasles
- Btuberculosis
- Chepatitis
- Dsmall pox
69The alternative pathway of complement activation is:
- AT lymphocytes dependent
- Bantibody independent
- Cantibody dependent
- DT lymphocytes independent
70Which of the immunoglobulins mediates the local immunity
- AlgA
- BlgM
- ClgG
- DlgD
- ElgE
71The formation of pharyngeal pseudomembrane is not indicative for
- Atuberculosis
- Bdiphtheria
- Cwhooping
- Dgas gangrene
72The most potent biological toxin known is
- Aclastridiumbotidinum exotoxin
- Bstaphylococcus aureus enterotoxin
- Cbacillus cereus toxin
- Dclostridium perfringes exotoxin
73The special staining method used for microscopic diagnosis of tuberculosis
- AGram
- BKlett
- CZiehl-Neelsen
- DMoller
74Cytopathic effect is
- Akilling of bacteria by viruses
- Babsorption of red blood cells by surface of cultured cells
- Cdamage of cultured infected cells and associated morphological change
- Dantigen-antibody reaction
75Viruses contain the following type of nucleic acid
- ADNA-single strained
- BDNA double strained
- CDNA or RNA
- Dboth DNA and RNA
76Hepatitis B virus is most often transmitted by
- Asexual contact
- Bair
- Cblood transfusion
- Dticks
77Varicellazinster virus is a member of
- Ahypersnviridae
- Bhepadnaviridae
- Cretroviridae
- Dpaenviridae
78Epstizin Bar Virus is the causative agent of:
- Ameasles
- Bmumps
- Crubella
- Dinfectious mononucleosis
79Sabin's vaccine against poliomyelitis is secretory immunity in the intestine
- Aa killed vaccine
- Ba toxoid
- Cmonovalent hysosome vaccine
80Spherical bacteria,arranged in cluster are known as:
- AStaphylococci
- BStreptococci
- CDiplococci
- DVibrios
81Which concentration of ethyl alcohol is the most effective one as disinfectant and antiseptic
- A95%
- B70%
- C50%
- D30%
82Penicillin specifically inhibits:
- Aprotein synthesis
- Bpeptidoglyconsynthesis
- Cnucleic acid synthesis
- Dformation of capsules
83Conjugation differs from transformation and transduction in that it requires a contact between the donor and the recipient:
- ATrue
- BFalse
84Which of the following structure is involved in bacterial attachment to cell surface?
- Acapsule
- Bflagella
- Cpilli
- Dmeasurants
85Bacterial growth medium that contains penicillins:
- Aminimal medium
- Bselective medium
- Cdifferential medium
86The antigen-antibody complex activates complement through:
- Aclassical pathway
- Balternative pathway
- Clectin pathway
87Complement is
- Aan acute phase protein
- Ban extracellular microbial factor
- Ca manose receptor
- Dmulticomponent humeral factor trigger enzyme cascade in innate immunity
88The unit of measurement of bacterial size is:
- Ananometer
- Bmicrometer
- Cmillimeter
- Dkilobase
89Bacterial growth curve is generally separated into
- Atwo distinct phase
- Bthree distinct phase
- Cfour distinct phase
- Dfive distinct phase
90Resistance to many antibiotics is carried by:
- AR plasmids
- Bsex pilli
- Cspores
- Dcapsules
91Which of the following structures are known to protect bacteria from phago... by white blood cells
- Aflagella
- Bspores
- Ccapsules
- Dribosomes
92Spherical bacteria, arranged in chains are known as:
- Astaphylococci
- Bstreptococci
- Cneisseria
- Dbacilli
93Endotoxins are associated with
- ACatalase production
- BFlagella in gram (-) bacteria
- CLPS (lipopolyshoccharide)
- DCapsules in gram (-) bacteria
94The antigenic typing of salmonella spp detects:
- AD, Vi and H antigens
- BProtein
- CM protein
- DEndotoxin
95Which of the following test is used to detect delayed type hypersensitivity
- AASO test
- BCFT
- CMantoux test
- DNone of the above
96Which are the most important immunoglobulins at the mucosal surfaces
- AIgA
- BlgM
- ClgD
- DlgG
97Salmonella spp is causative agent of
- Atyphoid fever
- Bcholera
- Cparatyphoid fever
- Dbacterial dysentery
98There are animal reservoirs for:
- Aleptosspinosis
- Bsalmonellosis
- Ccholera
- Ddiphtheria
99Bacteria could be cultured in artificial nutrient media
- ATrue
- BFalse
100The mean doubling time for most bacterium is
- A8 hours
- B24 hours
- C20-30 minutes
- D4 weeks
101Dark field microscopy is usually applied for
- Astained preperations with irreversion cell between cochser
- Bunstrained wet preparation with oil between the conduncer and the slide irreverSion
- Cunstained wet properations with water between the condenser and the slide
- Dultra thin reactions of tissue
102Which of the following component contain peptidoglycan?
- AGram(+) cell walls +F
- BDNA
- CFlagella
- DCytoplasmic membrane
103The clorax solution and ethyl alcohol are example of:
- Asterilizing agents
- Bdisinfection
- Cantibiotics
- Dbase analogs
104Which immunoglobin contain j chain
- AIgA and lgG
- BlgM and lgA
- ClgG and IgM
- DlgD and lgG
- ElgE
105Which of the following are DNA viruses?
- Aadenoviruses
- Bpicornviruses
- Cparamyxoviruses
- Dorthomyoviruses
106Which one is considered a vireal disease viral
- Aherpes simplex type 1
- Bherpes simplex type 2
- Crubella vire
- Dmedual vire
107Which of the following diagnostic markers persist in the blood stream of HBV infected individuals and is found an (imcatox) of infection
- AHBsAg
- Banti-HAV antibodies
- CH-2
- Dnone of the above
108All of the following statement about poliomyelitis are correct except:
- Avirus is transmitted mainly in respiratory droplets
- Bmost disease occur apparent sub-clinical infection
- Cpersistantviremiafam CNS involvement
- Dspinal poliomyelitis involves the anterior born cells of the spinal cord
109During the incubation period of the HBV infection which of the following viral diagnostic marker is most abundant in blood and is commonly used for diagnosis
- AHBSAg
- BAnti-HAV antibodies
- CAnti-HCV antibodies
110Influenza virus on RNA virus:
- ATrue
- BFalse
111Human herpes virus 2 is usually associated with:
- Agenital herpes
- Bmeasles
- Crubelia
- Derpes zoster
112Human immunodeficiency virus belongs to:
- Aadenoviridae
- Bretroviridae
- Ctogruviridae
- Dpoxviridae
113The presence of low levels lgG but not lgM antibodies to rubella virus in the newborn suggests:
- Acongenital infection
- Bautoimmune disease
- Cpresence of maternal antibodies
- Dallergy
114A four fold or greater increase in autoantibody titer,measured by appropriate available viral diagnostic test and performed on serum collected at time of disease onset and 14 days later would:
- Abe highly suggestive to the presence of the disease
- Bindicate previous infection in healthy person
- Cnot be sufficient for diagnosis
- Dnot be informative since the serum specimens were not collected at proper interval of time
115Current acute HAV infection is best diagnosed by the presence of?
- AHBgcAg
- Banti-HBcsntibodies
- CIgM anti-HAV
- Ddelta antigen
116Which of the following microorganisms lack a cell wall
- Aram positive cocci
- Bgram negative rods
- Crichetsia
- Dmycoplasma
117All of the following statement are characteristics for group A strepcoccus?
- Athey are rarely resistaned to paraisitis
- Bthey produce beta-hemolysis on blood agar
- Cthey are sensitive to bacitracin
- Dthey are of the normal environment fiera
118Herpes virus varicella is a member of (zoster) (varicella zoster virus is member of:
- Aherpes viridae
- Bpoxviridae
- Chepadnaviridae
- Dretroviridae
119Which of the following Viruses cause infection mononucleosis?
- AHerpes simplex 1
- BEpstein-barr-viruses
- CCMV
- DVaricella zoster virus
120Type 2 hypersensitivity reactions are
- Aanaphylactic and atopic
- Bcomlement-mediated cytolysis
- Cimmune-complexes mediated
- Dcell mediated with participation
121The causative agent of AIDS is:
- AHuman herpes virus
- BHaemophilus influenzae
- CHuman papilloma virus
- DHIV
122Which of the following components contain peptidoglycan?
- AGram (+) cell walls
- BGram (-) cell walls
- CDNA
- DCytoplasmic membrane
123Risus sardonicus refers to:
- Adiphtheria
- Bmeasles
- Ctetanus
- Dbotulism
124Slide agglutination test detects:
- Amicrobial antigens
- Bunknown
- Cviral particles
- Dbacterial phagocytosis
125Protein A is a surface protein covalently bound to most strains of
- Astaphylococcus aureus
- Bstaphylococcus epidermidis
- Cstreptococcus pyogenes
- Dstreptococcus viridans
126Which of the following interferons participate in the .... immune response?
- Ainterferon alpha
- Binterferon beta
- Cinterferon gamma
127The microbiological test that is widely used for the diagnosis of staphylococcal
- AAgglutination test type wide
- BAgglutination type ....oneresh
- CASO
- DCFT
128Which of the following statements are characteristics for group A streptococci
- Athey are rarely resistant to penicillin
- Bthey produce Beta-hemolysis on blood agar
- Cthey are sensitive to bacitracin
- Dthey are part of the normal intestinal flora
129Which of the following vaccines is of routine use?
- Aagainst smallpox
- Bagainst hepatitis
- Cagainst measles
- Dagainst mumps
130Which of the following vaccines is not of routine use anymore
- Aagainst smallpox
- Bagainst hepatitis B
- Cagainst measles
- D)against mumps (not* hangislkfarkliysacvpodur)
131Which are is consider venereal disease virus
- Aherpes simplex type 1
- Bherpes simplex 2
- Crubella
132The subspecies group are identified on the basis of
- Aarrangement of the bacteria on the preparations
- Btheir antigen
- Cgram staining
- Dtheir growth requirement
133The main pathogenic factor of clostridium tetani is
- Aendotoxin
- Bexotoxin
- Cspores
- Dcapsule
134RIA makes use of:
- Afluorescence labels
- Benzymes
- Cradioactive labels
- Dit is not labelled immune reaction
135Which of the following immunoglobulin is the principal immunoglobin in exocrine secretion?
- AlgM
- BlgG
- ClgD
- DIgE
- EIgA
136The causative agents of tetanus is:
- Aclostridium difficile
- Bclostridium botulinum
- Cclostridium perfingens
- Dclostridium tetani
137The positive coagulase test for staphylococcus aureus is indicated by:
- Acharacter of plasma
- Bclotting of plasma
- Cformation of red ring
- Dbeta hemolysis on blood agar
138This microorganism causes a sexually transmitted disease that can be diagnosed by demonstration of cytoplasmic inclusions in......?
- AChlamydia atrachomatis
- BCandida albicans
- CTrepomena pfedure
- DNeisseria gonorrhoeae
139Viridans streptococci:
- Acan cause neonatal sepsis
- Bare involved in urinary infection in females
- Care the most frequent cause of bacterial endocarditis
- Dcause zoonotic disease transmitted to humans primary by contact with animal urine
140Which of the following statement about microbiological diagnosis of diphtheria is correct
- AMicroorganisms are coagulase positive
- Bmicroscopy from culture on lofller’s medium or tallarite agar would reveal characteristic chinede letter formation
- Cmicroorganisms are impossible to be identified by Neisser stain because of their small size
- Dmicroorganisms are delicate and can be cultured only in ell culture
141Exotoxins play a determinant role in the pathogenesis of each of the following EXCEPT:
- Abotulism
- Bdiphtheria
- Ctetanus
- Dplaque
142Influenza virus belongs to:
- Ahepado viridae
- Borthomyxoviridae
- Cparamyxoviridae
- Dhypesviridae
143Which of the following is the leading cause of post transfusion hepatitis producing the highest frequency of chronic disease
- Ahepatitis A virus (HAV)
- Bhepatitls B virus (HBV)
- Chepatitis C virus (HCV)
- Dhepatitis D
144Which of the following immunoglobulins has the highest serum level in healthy adults
- AlgA
- BlgM
- ClgG
- DIgE
- EIgD
145Trepanemapallidum is the causative agent of:
- Atyphoid fever
- Bplague
- Csyphilis
- Dtuberculosis
146The pathogenesis and clinical of primary tuberculosis are characterized by
- Acell mediated response with macrophage and lymphocyte infiltrating the focus of infection
- Ba complement mediated immune response
- Ca humoral mediated immune response
- Dan absence of adaptive immune response
147Which form of plague is most likely to be transmitted from human to human:
- Atyphoidal
- Bsylvatic
- Cpneumonic
- Dulceroglandular
148Staphylococci differ from streptococci in:
- Agram reactivity
- Bcell diameter
- Cacid fast staining
- Dcatalase production
149All of the following characteristics of Salmonella typhimurium are true EXCEPT:
- Ahas a multianimal reservoir
- Bis one of the most common causes of enterocolitis
- Cferments lactose
- Dis a gram (-), molite, endotoxin bearing rod
150Which of the following characteristics concerning influenza A virus is correct
- Ait can always cause generalized infections
- Bit can always cause encephalitis
- Cit has the capacity to undergo shift and drift
- Dit has nonsegmented negative sense genoma
151Hepatitis A virus is most often transmitter by
- Asexual contact
- Bcontaminated food
- Cblood transfusion
- Dshared needles
152All of the following statements are characteristic for group A streptococci EXCEPT:
- Athey are rarely resistant to Penicillin
- Bthey produce beta-hemolysis on blood agar
- Cthey are sensitive to bacitracin
- Dthey are part of the normal intestinal flora
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- Microbiology MCQs 3rd Year Final- PMU
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