Flashcards
Week 5 Pharmacology and Pain
Cards in this deck (19)
- 1Acute painspecific and predisposing factor, limited duration
- 2chronic painongoing tissue injury, may persist after the original lesion has healed
- 3Nociceptive painpain following activation of normal pain fibres (e.g. tissue injury)
- 4Allodyniapain due to stimulus which wouldn't normally provoke pain e.g. cotton on skin
- 5Hyperalgesiaincreased response to stimulus which is normally painful
- 6Breakthrough panoccurs between regular doses of analgesics, reflects an increase in pain beyond control of baseline
- 7Incident painoccurs with physical activity, e.g. wound dressing
- 8NSAIDSibuprofen, aspirin
inflammatory, nociceptive pain
adverse effects:
GIT bleeding, worsening of asthma, CNS, headache, dizziness, kidney failure, fluid retention, elderly are vulnerable - 9NSAID interactionswarfarin and anticoagulants
diuretics and ACE inhibitors= tripple whammy - 10Opioidsused for acute and chronic pain
rapid onset of action - 11Opioid dosingdoses are age dependent, less dose for elderly, modify dose accordingly
- 12Opioid choicesacute surgical=fentanyl, morphine
chronic=oxycodone, morphine, methadone - 13Opioid mechanism of actionactivate opioid receptors (mu), decreasing transmission of pain impulse, neuronal cell no longer in an excitable state
- 14Disadvantages of opioids for acute painrespiratory depression, sedation score, nausea and vomiting
- 15Disadvantages for opioids for chronic paintolerance, dependence, elderly more vulnerable
- 16Tramadol(s4)
weak mu agonist
adrenaline and serotonin reuptake inhibitor
nausea a probelm - 17Antagonist: naloxonehigh affinity to mu receptor
used for reversal of opioid overdose
for resp depression
IV only, short half life - 18Targincombination of oxycodone (mu agonist) and naloxone (mu antagonist)
used to minimise constipation to decrease regular laxatives - 19Paracetomolanalgesic, antipyretic, weak anti-inflammatory
adverse effects: hepatotoxicity which is dose related
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- Nursing Flashcards on Week 5 Pharmacology and Pain, created by Elizabeth Then on 09/09/2017.
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- Elizabeth Then
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