Common Meds in Dentistry

Common Meds in Dentistry

1. CVD

   • Hypertension
     • Metroprolol
       • Beta Blocker
         • B-1 Adrenergic Receptor ANTAGONIST. Acts on receptors in heart ONLY, not lungs (asthma). Decreases HR, CO & BP. POstural Hhypotension an issue. DONT prescribe NSAIDS - Do the same thing so will double up. Dont us Mepivicaine as both metabolised by liver
     • Cilazapril
       • ACE Inhibitor
         • Stops ACE from converting Angiotensin1 --> Angiotensin2 (Vasoconstrictor) = Net Vasodialtion. Dry cough common, Angiodema 0.1-0.07%
   • MI, Stroke
     • Asprin
   • Atherosclerosis
     • Simvastatin
       • HMG-CoA Reductase Inhibitor
         • Decreases Total Serum Cholesterol. Prevents plaques progressing. Angiodema. Interactions w AB's & AF's

2. Pain

   • Paracetamol
     • Cox-2 Inhibitor
       • Not antithrombotic as cox-2 selective. Good for mild dental pain. Max dose 10x 500mg tabs/24hrs. May cause liver toxicity
   • Ibuprofen
   • Asprin

3. Inflammation

   • Ibuprofen
     • NSAID
       • Anti-inflammatory, Anlagesic, Antipyretic. Inhibits Prostaglandin synthesis = Decreases pain, heat, swelling etc. Careful not to OD.
   • Asprin
     • Cox Inhibitor
       • Anti-inflam, Anti-pyretic, Anti-platelet. Increases bleeding after exo, endo etc

4. Asthma

   • Salbutamol
     • B-2 Adrenergic Receptor AGONIST
       • For Treatment of Bronchospasms in Asthma. "Reliever" Dry mouth, Oral Candidosis. Careful with NSAID interaction. B-1 agonsit NSAIDS harmful in asthma attacks

5. GORD/ Gastric Ulcers

   • Omeprazol
     • Proton Pump Inhibitor
       • Decreases Acid Production in Stomach. Px may have ^^ Erosion in mouth - Occlusal Max Molars. May interfere w antifunglas

6. Contraception

   • OCP
     • Oestrogen + Progesterone
       • Some Antibiotics/ Antifungals may affect OCP function. Usually decreases its absorption & increases its secretion via plasma binding protein.

7. Osteoperosis

   • Alendronate
     • Bisphosphonate
       • Decreases Bone turnover How? osteoblast > osteoclast activity Can cause bisphosphonate ONJ Painless necrosis usually after exo or apical infection