Respiration

Respiration

1. Glycolysis

   • Glucose (6C)
     • Glucose phosphate (6C)
       • Fructose phosphate (6C)
         • Fructose biphosphate (6C)
           • 2x Triose phosphate (3C)
             • 2x GP (3C)
               • 2x Pyruvate (3C)
                 • 2ADP
               • 2ATP
             • 2ATP
               • 2rNAD
             • 2ADP
               • 2NAD
         • ATP
         • ADP
     • ATP
     • ADP
   • Yield: 2Pyruvate 2ATP (net) 2rNAD
   • Occurs in the cytoplasm of all cells
   • DOES NOT REQUIRE OXYGEN
   • purpose is to create pyruvate for link reaction

2. Link Reaction and Krebs Cycle

   • Pyruvate
     • Acetyl CoA
       • Acetate (2C)
         • Citrate (6C)
           • 5C Compound
             • 4C Compound
               • 4C Compound
                 • 4C Compound
                   • Oxaloacetate (4C)
                   • rNAD
                 • rNAD
               • ATP
             • CO2
               • rNAD
           • CO2
             • rNAD
       • CoA
     • CO2
   • Occurs in the matrix of mitochondria
   • Purpose is to create rNAD and rFAD for ETC

3. Electron Transport Chain

   • • • • 2e-
           • 1/2 O2 + 2H+
             • H2O
               • MATRIX
         • H+
         • H+
         • H+
           • H+
         • INTERMEMBRANE SPACE
         • • H+
           • ADP + PI
             • ATP
       • H+
       • H+
       • H+
       • H+
       • H+
     • rNAD/rFAD
       • NAD/FAD
     • 2H
       • 2e-
       • H+
         • H+
           • H+
   • Hydrogen atoms are split into protons (H+) and electrons (e-)
     • Electrons move along the ETC, losing energy
       • This energy is used to actively transport protons from the matrix to the intermembrane space
         • Some energy is used to combine ADP + Pi to ATP
           • Electrons combine with protons to form water (FINAL ELECTRON ACCEPTOR)