Quiz
Clinical Immunology Final MCQs- 4th Year- PMU
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Questions in this quiz (58)
1Which of the following methods is suitable for detectin of serum globulins?
- ANephelometry
- BRadial immnodiffusion by manchini
- CTurbidimetry
- DNBT-test
- EThe mantoux test
2Type II allergic reations are realized by
- Aanaphylaxis
- Bcomplement-mediated cytolysis
- Cimmune complexes
- Dinfectious immunity
3Monoclonal antibodies are
- Apure population of immunoglobulins with same structure ant antigen specifity
- Balbumins that are coded from other group of genes
- Cmixed population of immunoglobulins with same structure, but different antigen specifity
- Dsubstrate causing expression of immunoglobulins from other class in B-cells
4Which immunological method is not proper for detecting of specific IgE
- AImmuno-enzyme(ELİSA, immuno-blot technique)
- BClassical ones(agglutination, precuipitation)
- CFloucytometry
- DChemilluminescence
5Low levels of IgA are found in case of
- Aallergic reaction
- Bchronic granulamatosis disease
- Cselective IgA deficit
- Dmacro-globulinemia
6Auto immune disease due to antibodies could be a result of (point the wrong answer)
- Aforming of antigen-antibody complexes
- Bantibodies that blockade cell receptor
- Cantibody-depended cell-mediated cytotocicitty(ADCC)
- Dcell-mediated reaction
7The name of resident macrophages in liver is
- Aostephages
- Blagerhance cells
- Ckupfer cells
- Dmicroglial
8EBV can cause
- AHepatoma
- BNasopharyngeal carcinoma
- CBurkit lymphoma
- DAdenocaqrcinoma pulmonis
9Which of the following indicators is the most important in case of detecting of immune status in AIDS
- ANBT test
- BAnti-DNA antibodies
- CCD4/CD8 index
- DThe bence-jones protein
10System lupus erythematosus
- Ais caused by mutations in ds-DNA
- Bis revealed with many symptoms and affects many organs
- Cis an example of T-cell mediated disease
- Dis a result of generating of immune complexes
11The opsonisation is a process of
- AIngestion and destruction of an antigen from phagocyte
- BOf covering of antigen with antibodies in purpose to ease phagocytosis
- COf covering of antigen with complement in purpose to ease phagoytosis
- DObtaining of monoclonal antibodies
12Connect with arrows allergic diseases with relevant types allergic reactions:
Type [blank_start]3[blank_end] - serum-disease
Type [blank_start]4[blank_end] - contact dermatitis
Type [blank_start]1[blank_end] - anaphylaxis
Type [blank_start]2[blank_end]- hemolytic disease of newborn- A3
- B1
- C2
- D4
- E4
- F1
- G2
- H3
- I1
- J2
- K3
- L4
- M2
- N1
- O3
- P4
13The mature B-lymphocytes expresses onto their surface
- AIgM and IgD
- BIgM and IgA
- CIgD and IgE
- DIgG and IgD
14The lymphocyte infiltration of thyroidea is typical for
- AThe hashimoto thyroitidis
- BEuthyroid struma
- CHemolytic anemia
- DTuberculosis
15The electrophoresis is
- Aradial immunodiffusion in gel
- Bseparation of molecules in electric field
- Ccomplement fixation reaction
- Delectroimmunodiffusion
16I type allergic reactions are
- AImmunocomplex
- BCytotoxic
- CIgE mediated
- DCell mediated
17Connect with arrows autoimmune diseases from the left side with relevant characteristics from the right side: wide with relevant characteristics
a. Multiple sclerosis [blank_start]6[blank_end]
b. SLE [blank_start]4[blank_end]
c. Myasthenia gravis [blank_start]5[blank_end]
d. Pernicious anemia [blank_start]1[blank_end]
e. Hashimoto thyoiditis [blank_start]2[blank_end]
f. Hemolytic anemia [blank_start]3[blank_end]
1. autoantibodies against parietal cells of stomach ans intrinsic factor and as a result of this doesn't absorb Vitamin B12
2. autoantibodies against thyroglobuline and thyroid peroxidase
3. antibodies against epitopes of red blood cells
4. antibodies against nucleus antigens
5. antibodies against acetylcholine
6. antibodies against morbidly antigens in liquor and serum, depressed reactions of delayed type hypersensitivity against measles antigens- A6
- B1
- C2
- D3
- E4
- F5
- G4
- H1
- I2
- J3
- K5
- L6
- M5
- N1
- O2
- P3
- Q4
- R6
- S1
- T2
- U3
- V4
- W5
- X6
- Y2
- Z1
- AA3
- AB4
- AC5
- AD6
- AE3
- AF1
- AG2
- AH4
- AI5
- AJ6
18The monoclonal antibodies, connected with diphtheria toxin could be used for
- Atumour diagnosis
- Bimmunostimulation
- Cimmunosupperession
- Dimmunotherapy of tumors
19The defensins are
- Agrowth factors
- Bantimicrobial peptides in granules of neutrophils
- Ccytokines-mediators for immune response
20What is the mechanism of III type allergic reactions
- Aanaphylaxis
- Bcomplement-mediated cytolsis
- Cimmune complexes
- Dinfectious immunity
21Which of the following tumour markers are connected with melanoma maligna?
- ACA-15-3
- Bgp 120
- CS100B
- DMART-1Melan A
22Immuno-scintigraphy uses monoclonal antibodies against tumour antigen connected with
- AFITC
- BRhodamine
- CIodine 131, technetium
- DEnzyme
23INF-γ is produced by
- AActivated T lymphocytes
- BFibroblasts
- CB-lymphocytes
- DLeucocytes
24What kind of auto-antibodies we find in patients with insulin-depended sugar diabetes?
- ANucleus
- BThyroid microsomes
- CIgG molecules
- DIsland cells of pancreas
25Rejection of a transplantant due to pre-forming antibodies in recipient is defined as
- AHyper acute rejection
- BAccelerated
- CAcute
- DChronic
26What of the following possesses the most expressed oncogenic potential
- AInfluenza virus type A
- BEbola virus
- CEBV
- DPolioviruses 1,2 ,3
- EHPV
27Is the following correct?
Active immunity is a nospecific and is an ancient form of defense and lower degree of effectiveness?- ATrue
- BFalse
28Type IV allergic reactions are realized by means of
- Aanaphylaxis
- Bcomplement-mediated cytolysis
- Cimmune reactions
- Dinfectious immunity
29True hypersensitivity reactions start usually after
- A15-30 minutes
- B48 hours
30Which of the following characteristics does not belong to the Burkit lymphoma?
- AT-cell neoplasma
- BIs a non-hodgkin lymphoma
- CHas a connections with EBV
- DIs a B-cell lymphoma
31Antigen presenting cells are
- ADendrite cells and macrophages
- BT-lymphocytes
- CB-lymphocytes
- DPolymorphy-nuclear cells
32We could use the mantoux test in diagnosis of (point two diseases)
a- [blank_start]Tuberculosis[blank_end]
b- [blank_start]Leprosy[blank_end]- ATuberculosis
- BLeprosy
33Which of the following factors belong to the innate immunity?
- APhagocytosis
- BT-lymphocytes
- CComplement, mucin, a-and b inferferons
- DAntibodies
- ESkin, mucus, normal flora
- FB-lymphocytes
34What we could use as a subsrrate for detection of antinuclear antibodies throguh IFA?
- Arat liver
- Brat kidney
- Crat stomach
- Dhep2 cell line
35Which of the pointed immunological parameters is most important for detection of multiple myleoma?
- ANBT test
- BAnti-DNA antibodies
- CCD4/CD8 index
- DThe Bence-jones protein
36The most popular techniques for detection of antinuclear antibodies are
- AAgglutination
- BIndirect immunofluorescence
- CNeutralization test
- DThe complement fixation test
- EELISA
- FDirect immunofluorescence
37CD3 molecule is a marker for
- ANK cells
- BMacrophages
- CImmunocompetent T lymphocytes
- DMature B-lymphocytes
38The accelerated reaction for rejection of transplantant is revealed
- AIntra-operative or immediately after operation
- B24-to 72 hours after transplantation
- CTill the third month
- D3 month after the transplantation
39which of the following immunological indexes ids the most important for patients with chronic granulomatous disease?
- ANBT test
- BAnti DNA antibodies
- CCD4/CD8 index
- DThe Bence-jones protein
40CEA is increased in case of
- Anasopharyngeal carcinoma
- Bthe Burkit lymphoma
- Cgatro-intestinal tumors
- Dsmokers
41Which of the following is connected with damage of humoral immunity?
- ADi-George sydrome
- BAgamaglobulinemia of Bruton
- CChronic candidosis of skin and mucus
- DAngioedema hereditaria
42How many are complement activating ways?
- Aone
- Bthree
- Ctwo
- Dfour
43The complement activation occurs via three pathways which are:
1. [blank_start]Classical[blank_end] pathway
2. [blank_start]Alternative[blank_end] pathway
3. [blank_start]Lectin[blank_end] pathway- AClassical
- BAlternative
- CLectin
44The “respiratory burst" is related to
- AHumoral immunity
- BCellular immunity
- CPhagocytosis
- DNK-cells function
45The immune competence of T-lymphocytes is acquired in
- AThyroidea
- BBone marrow
- CThymus
- DMALT
46What expresses the CD8 molecule?
- AMacrophages
- BAntigen presenting cells
- CCytotoxic T-lymphocytes
- DT- suppressors
47What is human cell receptor for human immunodeficiency virus (HIV)?
- ACD3 molecule
- BCD8 molecule
- CCD4 molecule
- DCD19 molecule
48Point the WRONG answer:
Gamma interteron is produced by:- ANon-activated macrophages and mastocytes
- BLeucocytes and Fibroblasts
- CActivated macrophages and NK cell
- DLymphocytes
49The determination of functional activity of the complement might be done by
- AImmune histochemical methods
- BReaction neutratisation
- CCH50 test
- DMicro haemagglutination
50CD4 molecule is situated on the surface of the
- AMonocytes
- BT-helpers
- CCytotoxic T-lymphocytes
- DPlasmocytes
51The presence of the antigen together with the MHC-II class molecules is realized by
- ADendrite cells and macrophages
- BCytotoxic T-lymphocytes
- CB-lymphocytes
- DPlasmocytes
52A B-cell can synthesise some different antibodies with different species of the antigen
- ATrue
- BFalse
53After the antigen stimulus the mature B-lymphocytes are transformed into
- Acytotoxic cell
- Bimmunocompetent cell
- Cplasmocyte
54What tests are for evaluation of the phagocytic activity?
- AFlow cytometry of detection of oxidative burst
- BSerum levels of immunoglobulins
- CCD4/CD8 index
- DNBT test
55Paraproteinemias are detected in
- AMultiple myeloma
- BReiter's Syndrome
- CWaldenstrom macroglobulinemia
- DChronic lymphoid leukemia
- ESLE
56Last cells, incapable to divide are
- APlasmocytes
- BNeutrophils
- CT-lymphocytes
- DB-Iymphocytes
57What do the mature B-lymphocytes express on their surface?
- AlgM and IgD
- BIgD ant IgE
- CIgM and IgA
- DIgG and IgD
58How do CD8 eliminate their targets?
- Aafter recognition of antigen, connected with MCH-I class molecule
- Bafter recognition of antigen connected with MCH-II class molecule
- Cvia activation of an alternative way of complement
- Ddue releasing of interferon
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- Clinical Immunology Final MCQs- 4th Year- PMU
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