Quiz
Pathology Exam 1
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Questions in this quiz (45)
1What type of cellular adaptation is seen in this picture? (Hint: it's the prostate)
- AHypertrophy
- BHyperplasia
- CMetaplasia
- DAtrophy
2What type of cellular adaptation is seen in this organ?
- AHypertrophy
- BHyperplasia
- CMetaplasia
- DAtrophy
3The heart can undergo both hypertrophy and hyperplasia.
- ATrue
- BFalse
4What type of cellular adaptation is seen in this picture?
- AHypertrophy
- BHyperplasia
- CMetaplasia
- DAtrophy
5Which of the following is INCORRECT regarding metaplasia?
- AMost common change is columnar --> squamous
- BThe new cell type is better capable of enduring the stressful environment
- CIt is an irreversible process
- DIt occurs in respiratory epithelium
6The thyroid pictured on the right has undergone hyperplasia and hypertrophy.
- ATrue
- BFalse
7Myocardial hypertrophy is always pathologic.
- ATrue
- BFalse
8This patient with tonsilitis shows cells that have undergone:
- AHypertrophy
- BHyperplasia
- CMetaplasia
- DAtrophy
9Vitamin A deficiency is associated with atrophy because the cells need Vitamin A for differentiation of specialized epithelium.
- ATrue
- BFalse
10Which of the following is not associated with Hypoxemia?
- AInsufficient Oxygen
- BIschemia
- CHyperventilation
- DPneumonia
11Budd-Chiari Syndrome is an example of hypoperfusion of the tissue with blood leading to reduced supply of oxygen and substrates for glycolysis.
- ATrue
- BFalse
12Methemoglobinemia can cause hypoxemia by creating a ventilation perfusion mismatch.
- ATrue
- BFalse
13Which of the following is NOT associated with reversible changes of cell injury.
- AKaryorrhexis
- BER swelling
- CPlasma membrane blebbing
- DMyelin figures in the cytoplasm
14Which term best describes the nuclear changes shown?
- APyknosis: shrinkage and increased basophilia due to chromatin condensation
- BKaryorrhexis: fragmentation of pyknotic nuclei
- CKaryolysis: Decreased nuclear basophilia due to DNA degradation by nucleases
- DLoss of nuclei
15What are the 2 main events that characterize irreversible cell injury ?
- ADisturbances in the membrane function and activation of the complement system
- BGlycogenolysis and increased pH in the interstitial fluid
- CMitochondrial dysfunction and breakdown of cell membrane
- DLoss of microvilli and detachment of ribosomes from the ER
16These hepatocytes have undergone reversible cell injury.
- ATrue
- BFalse
17What type of necrosis is demonstrated in these images?
- AGangrenous
- BCoagulative
- CFat
- DCaseous
18Liquefactive necrosis only occurs in the brain.
- ATrue
- BFalse
19What is the type of necrosis demonstrated by these images?
- ALiquefactive
- BFat
- CCoagulative
- DCaseous
20Wet-gangrene is a superimposed bacterial infection in an area with necrosis due to loss of blood supply (coagulative necrosis).
- ATrue
- BFalse
21Which of the following is NOT associated with the generation of reactive oxygen species?
- ARadiation
- BThe electron transport chain
- CLeukocytes
- DMethylene blue
22Ischemia-Reperfusion injuries can happen when blood flow is restored to ischemic viable tissue which is reversibly injured.
- ATrue
- BFalse
23Antioxidants, chelators, and catalase are all examples of mechanisms that can remove ROS
- ATrue
- BFalse
24Dystrophic calcification occurs in dead/dying tissues in the absence of systemic hypercalcemia. Cell loses ability to regulate intracellular calcium and crystalline calcium phosphate forms.
- ATrue
- BFalse
25Which of the following is an exogenous pigment?
- AHemosiderin
- BLipofuscin
- CCarbon
- DMelanin
26Which disease of premature aging has mutation in LMNA gene. The defective protein Progerin accumulates in the nucleus. Male pattern baldness, atherosclerosis and CAD are common with lifespans less than 10 years.
- ABernard Soulier
- BHutchinson Guilford Progeria
- CFactor V Mutation/Leiden Mutation
- DKleinfelter's Syndrome
27Werner Syndrome is a disease of premature aging due to a mutation in the WRN gene, which plays a role in telomere length maintenance and processing DNA damage.
- ATrue
- BFalse
28Inflammation is a hallmark of apoptosis.
- ATrue
- BFalse
29Which of the following are not associated with physiologic apoptosis?
- AThe de-webbing of fingers during embryogenesis
- BThe shedding of the endometrium during the menstrual cycle
- CThe elimination of mutated genes that accumulate misfolded proteins
- DThe elimination of self-reactive lymphocytes
30Which of the following is NOT a main pathway in the initiation of apoptosis
- AMitochondrial
- BDeath-receptor mediated
- CUbiquitin degradation
- DCytotoxic CD8+ T-cell
31Uterine serous carcinoma is an aggressive cancer with a possible alteration of p53 in the pathogenesis. Mutated p53 is incapable of inducing apoptosis and therefore cells with damaged DNA can continue to proliferate and undergo malignant transformation.
- ATrue
- BFalse
32Which of the following is not a trigger for inflammation?
- AInjury
- BInsult
- CIntegrins
- DInfection
33Which of the following is a component of the acute inflammatory response?
- AResponse time of days to years
- BVascular proliferation and scarring
- CFluid and plasma exudation
- DHigh specificity
34Which statement is incorrect?
- ACalor and rubor are caused by vasodilation
- BTumor is due to decreased vascular permeability
- CDolor is an outcome of the kinin cascade
- DHistamine release can cause rubor
35Which is incorrect regarding platelets?
- AThey are formed from megakaryocytes in the bone marrow
- BThey contain a pyknotic nuclei
- CThey contain dense granules and alpha granules
- DThey are part of the primary hemostatic plug
36Which cells are likely to be seen in an allergic reaction?
- AMast Cells
- BEosinophils
- CMacrophages
- DLymphocytes
37Which statement is correct regarding mast cells?
- AThey have cytoplasmic granules with lysosomal enzymes, cytokines, and major basic protein
- BThey are also called polymorphonuclear cells
- CThey are widely distributed throughout connective tissue
- DThey can differentiate into dendritic cells
38Transudates are high in protein and come from inflammation.
- ATrue
- BFalse
39Which is not a pathway in the complement system?
- AClassical Pathway
- BAlternative Pathway
- CMitochondrial (Intrinsic) Pathway
- DLectin Pathway
40Which factors are invovled with chemotaxis, recruitment and activation of leukocytes?
- AC3a & C5a
- BC5b complexs
- CC3a & C3b
- DIgG & IgM
41Paroxysmal Nocturnal Hemoglobinuria (PNH) results in complement-mediated lysis of RBCs due to which of the following mechanisms/defects?
- ALoss of Hageman Factor (Factor VII)
- BDeficiency of the C1 inhibitor
- CExcessive production of the Membrane Attack Complex
- DDeficient plama lectin the the mannose binding lectin pathway
42Which of the following is not a step in leukocyte Recruitment?
- AAdhesion
- BTransmigration
- CTransformation
- DMargination
43During the resolution phase of acute inflammation, neutrophils undergo apoptosis.
- ATrue
- BFalse
44The umbilical cord taking longer to separate after the baby is born may be a sign of Leukocyte Adhesion Deficiency.
- ATrue
- BFalse
45Impaired fusion of phagosome with lysosomes, disordered trafficking of organelles, giant granules in leukocytes, and neutropenia are all symptoms of Chediak-Higashi Syndrome.
- ATrue
- BFalse
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- Description
- Practice exam for pathology exam 1.
- Author
- K-WOW
- Language
- English
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