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Bacterial colonisation & Infection

Jacob Coe FoM Year 1 University - Medicine Inglés 14 fichas

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  1. 1Define: Colonisation.the presence of bacteria in/on a host with growth & proliferation without invasion.
  2. 2Define: Virulence.measure of the severity of the disease caused by an agent of infection.
  3. 3Name an infection with spreads directly (person-to-person).Mycobacterium tuberculosis
    SARS-CoV-2
  4. 4Name an infection which spreads from vector to vertebrate.Plague
    Yellow fever
  5. 5Name an infection which spreads frmom a vertebrate.Rabies
    Q fever
  6. 6Name an infection spread from a vector.Malaria
  7. 7Suggest a pathogen located in the following areas: a) GI tract b) Vagina c) Skin d) Naso/Oropharnyxa) E. coli
    b) E. coli
    c) Staphylococcus aureus
    d) Staphylococcus aureus
  8. 8In what 3 ways can normal flora be protective?1. Non-specific stimulation of immune responses.
    2. Competitive bacterial interference.
    3. Niche occupation.
  9. 9Suggest 3 factors which may promote colonisation.1. Pili
    2. Fimbriae
    3. Adhesins
  10. 10What are pili & fimbriae?Long, thin protein polymers.
  11. 11Define: Invasiveness.ability of a pathogen to invade.
  12. 12Suggest 3 factors which ease invasion.1. Colonisation factors
    2. Secreted factors that enable invasion into cells.
    3. Evasion of immune system
  13. 13Describe the invasion process of Gonococci.Gonococcus adheres to & invades columnar epithelium.
    Replicates in basement membrane.
    Invades into cells via disseminating from blood.
    Induces an inflammatory response --> symptoms.
  14. 14Describe the process of invasion of Streptococcus pneumoniae.Nasopharyngeal transmission.
    Interacts with complement ==> impairs neutrophil recruitment (evading immune).
    Mucus degradation.
    Pili-mediated binding to host cell receptors.

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University - Medicine (Microbiology) FoM Year 1 Fichas sobre Bacterial colonisation & Infection, creado por Jacob Coe el 15/01/2022.
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Jacob Coe
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