Disorders of hepatic & Biliary Fx

Disorders of hepatic & Biliary Fx

1. Hepatotoxic Disorders

   • Drug & Hormone metabolism
     • Phase 1 Reactions
     • Phase 2 reactions
     • P-Glycoproteins
   • Drug Induced Liver Disease
     • Direct Hepatotoxic Injury
     • Idiosyncratic reactions
     • Chronic Hepatitis

2. Viral Hepatitis

   • Hepatitis a
   • Hepatitis B
   • Hepatitis C
   • Hepatitis D
   • Hepatitis E
   • Chronic Viral Hepatitis

3. autoimmune Hepatitis

   • Clinical Manifestations
   • Dx
   • Treatment

4. Intrahepatic Biliary Disorders

   • Primary Biliary Cirrhosis
     • Clinical Manifestations
     • Treatment
   • Secondary Biliary Cirrhosis

5. alcohol induced Liver Disease

   • alcohoi Metabolism
   • alcoholic Liver Disease
   • Nonalcoholic Fatty Liver Disease
     • Patho
     • Clinical Manifestations
     • Treatment

6. Cirrhosis, Portal Hypertension, & Liver Failure

   • Cirrhosis
     • Clinical Manifestations
   • Portal Hypertension
     • ascites
     • Splenomegaly
     • Portosystemic Shunts
   • Liver Failure
     • Clinical Manifestations
     • Disorders
       • Hematologic
       • Endocrine
       • Skin
       • Hepatorenal
       • Hepatic Encephalopathy
     • Treatment

7. Liver Cancer

   • Primary Liver Cancer
     • Hepatocellular Carcinoma
     • Cholangiocarcinoma
   • Secondary: Metastatic Tumours