Flashcards
Chapter 15
Cards in this deck (39)
- 1innate defense (specific or nonspecific?)nonspecific
- 2adaptive defense (specific or nonspecific?)specific
- 3"non self" moleculesAntigens (Ag)
- 4Ag: usually large and ___ to the bodyforeign
- 5___ immunity: uses___ produced by the B cellsHumoral
Antibodies - 6___-____ immunity: uses T cellscell-mediated
- 7activation of innate immunity triggered by ____PAMPs (Pathogen-associated molecular patterns)
- 8LPS from gram ____ bacteria cell membranenegative
- 9_____ from gram positive bacteria cell wallpeptidoglycan
- 10How do immune cells recognize PAMPs?TLRs (toll-like receptors)
- 11PAMP-TLR complex eventually leads to ___inflammation
- 12inflammation initiates ____ phagocytosis by blood phagocytesnonspecific
- 134 main characteristics of inflammationpain, redness, swelling, warmth
- 14to initiate inflammation, cytokines activate ___ cells near the damaged areamast
- 15mast cells release ____ which ____ blood vessels and ___ cell membrane permeabilityhistamine
dilates
increases - 16another word for extravasationdiapedesis
- 17chemotaxis: recruits _____ (in the blood) which become ____ in the tissuemonocytes
macrophages - 18cytokines induce _____ of bronchi and bronchioles for protectionconstriction
- 19Phagocytosis: degradation of bacteria by ___macrophages
- 20tissue damage--> expressed _____--> leads to ____-->inflammationDAMPs
innate immunity - 21macrophages responsible for pus formationneutrophils
- 22order of phagocytes to arrive at site of infection1=neutrophils
2=monocytes/macrophages
3= T lymphocytes for specific immunity - 23body temperature regulated by the ___hypothalamus
- 243 ways to induce feverLPS
Interleukins (IL)
cytokines alter the set point - 253 effects of fevernonspecific decrease in bacteria
increase in neutrophil activity
increase in interferon production - 26interferons are ____ produced by cells with a ___ that offer short-term, ____ resistance to viral infectionpolypeptides
virus
non-specific - 27main effect of interferonsincrease overall immune activities
- 28B cells: named after ___ of Fabriciusbursa
- 29b cells= ____ cells and plasma cellsmemory
- 30t cells= of ___ originthymus
- 31HIV virus attacks _____ t cellshelper
- 32B cells= Ab _____ expansion of B cell ___->progeny become memory or plasma cellsreceptors
clones - 33___ cells=factoryplasma
- 34Ab structure: 2 ___ chains and 2 ____ chains each chain contains ___ (Fc) and ___ (Fab) fragmentsheavy
light
constant
variable - 353 Ab classificationsIgG=main in circulation
IgA=main in external secretions in mucosal area
IgE=allergic symptoms - 363 main T-cellsKiller
Helper
Suppressor - 37Killer (____) T cells: secrete ____ (leads to lysis) and _____(destroys victim's DNA)cytotoxic
perforins
granzymes - 38Helper T cells: increase responses of ___ and ____ cellsKiller T cells
B - 39Suppressor T cells: protect against ____ responsesautoimmune
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- VPHY 3100 (Exam 4) Flashcards on Chapter 15, created by Diamond Sapphire on 20/04/2018.
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- Diamond Sapphire
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