Flashcards
Pathophysiology (Disorders of White Blood Cells and Lymphoid Tissues)
Cards in this deck (23)
- 1List the three granulocytesneutrophils, basophils, eosinophills,
- 2List all the cells that rise from a myeloid stem cell-neutrophil
-basophil
-eosinophill
-platelets
-erythrocytes
-monocytes (from monoblasts) - 3List all the cells that rise from a Lymphoid stem cell-Natural killer cell
-t-cell
-b-cell (plasma cell) - 4what is the path of development of a neutrophil?1) Pluripotent stem cell in the bone marrow>Myeloid stem cell-->Myeloid blast --> Promyelocyte-->neutrophilic myelocyte-->neutrophilic metamyelocyte-->neutrophilic band cell-->Granulocyte --> neutrophil (released into circulation when needed)
- 5what is the path of development of a basophil1) Pluripotent stem cell in the bone marrow>Myeloid stem cell-->Myeloid blast --> Promyelocyte-->neutrophilic myelocyte-->neutrophilic metamyelocyte-->neutrophilic band cell-->Granulocyte --> basophil (released into circulation during allergic and hypersensitive reactions)
- 6what is the path of development of an eosinophil1) Pluripotent stem cell in the bone marrow>Myeloid stem cell-->Myeloid blast --> Promyelocyte-->neutrophilic myelocyte-->neutrophilic metamyelocyte-->neutrophilic band cell-->Granulocyte --> eosinophil (released into circulation during allergic reactions and parasitic infection)
- 7what is the development path of a B lymphocyte/plasma cell1) Pluripotent stem cell in the bone marrow
2) Lymphoid stem cell
3) lymphoblast
4)prolymphocyte
5)B-lymphocyte (in bone marrow)
6) plasma cell (then moves to lymphoid tissue to proliferate) - 8what is the development path of a T lymphocyte?1) Pluripotent stem cell in the bone marrow
2) Lymphoid stem cell
3) lymphoblast
4)prolymphocyte
5)T- lymphocyte (in lymphoid tissue) - 9what is the development path of a monocyte/macrophage1) Pluriponent stem cell in the bone marrow
2) Myeloid stem cell
3)Promonocyte
4) monocyte (released into blood stream)
5) macrophage - 10what is the function of a neutrophildamage control (initial leukocyte releases at injury. Works at clearing cell debris and invading microbes)
- 11what is the function of a basophil?response in allergic and hypersensitive reactions
- 12what is the function of an eosinophill?response to allergic reactions and parasitic invasion
- 13what is the function of a B-lymphocyte?to form plasma cell (which produce antibodies) and take place in humoral-mediated immunity
- 14what is the function of a T-lymphocyte?activate other immune cells and help with cell-mediated immunity
- 15what is the role of the lymphoid tissues?-mature lymphocytes
- 16Define "leukopenia"decrease in the absolute number of leukocytes in the blood
- 17Define "neutropenialow number of neutrophils in the blood
(mild:1000-1500/microliter)
(moderate: 500-1000/microliter)
(severe: less than 500/microliter) - 18define "granulocytopenia"decrease in granulocytes
- 19define "aplastic anemia"anemia, throbocytopenia and/or agranulocytosis induced by affected myeloid cells
- 20what are congenital causes of neutropenia?-Kostmann syndrome (inherited autosomal recessive)
-Periodic/cyclic neutropenia (autosomal inherited, possible impaired feedback regulation) - 21what are causes of aquired neutropenia-aplastic anemia
-cancer treatment (radiation/chemotherapy)
-nonmyelogenous leukemia
-lymphoma
-autoimmune issues - 22Define "mononucleosis"lymphoproliferative disorder, characterized by Epstein -Barr virus
- 23describe the pathogenesis of mononucleosis-transmitted through bodily fluid infected by Epstein-Barr virus
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- colle mooge/professional Pathophysiology Flashcards on Pathophysiology (Disorders of White Blood Cells and Lymphoid Tissues), created by Pip Fraggle on 12/10/2015.
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- Pip Fraggle
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