Flashcards
Viral Infections
Cards in this deck (16)
- 1Sizesmaller than bacteria - implications in diagnosis as can't be seen by light microscopy
- 2Composition Viral proteins (“naked” viruses)
Host lipid bilayer embedded with viral proteins
(“enveloped” viruses) - 3Shapes icosahedralproteins assemble to form particle - papillomavirus
- 4Shapes irregularmembrane surrounds particle - influenza virus
- 5Shapes bacteriophage T4more complex - different components and function
- 6Shapes near-sphericalViral proteins decorate an envelope derived from host membrane
corona virus - RTI - SARS - 7Nucleic acidDNA
RNA - 8Enzymessome carry them for replication and to aid escape
- 9Replication Replication of the genome
Formation of new particle
Escape and infection of a new host cell - 10Diagnosisclinical symptoms - growth in vitro - electron microscopy - analyse response of patient - molecular methods
- 11TransmissionPerson to person (aerosols/skin contact/sexual/blood/faecal-oral) - vector based (
- 12Influenzaneg. strand RNA - segmented genome - proteins at envelope surface - Haemagglutinin – sialic acid binding protein
Neuraminidase – aids assembly process - Antigenic drift vs antigenic shift
Problems in control
Avian reservoirs - 13other examples Hepatitis viruses
Hepatitis A
Single stranded RNA virus
Faecal-oral transmission
Rarely causes serious liver disease
Seropositivity is common suggesting common
exposure
Well controlled with vaccine - 14Hep B Double stranded DNA virus
Body fluid transmission often through blood
Acute, serious liver disease
Chronic infection linked to hepatocarcinoma
Vaccine offers hope for control but a global
problem - 15Hep CSingle stranded RNA virus
Body fluid transmission often through blood
Mild early in infection but often chronic liver
disease develops
Chronic infection linked to hepatocarcinoma over
several decades
Only transmission-based control at present - 16HIVRNA retrovirus
Immunosuppressive effects
Major global challenge to health
Progression can be controlled with drugs
Importance of education
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- Microbiology (Viruses) Flashcards on Viral Infections, created by NCadden on 05/05/2013.
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- NCadden
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