Neutrophil Maturation

Stacym09
Mind Map by Stacym09, updated more than 1 year ago
Stacym09
Created by Stacym09 over 6 years ago
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Hematology Mind Map on Neutrophil Maturation, created by Stacym09 on 10/05/2013.
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Resource summary

Neutrophil Maturation
1 Myeloblast

Annotations:

  • -makes up 3% of circulating nucleated cells in BM -15-20 um -NC ratio 5-7:1 -nucleus has fine chromatin, 2-5 nucleoli and is round to oval -cytoplasm is basophilic and agranular
1.1 Promyelocyte

Annotations:

  • -larger than myeloblasts, 12-24 um -2% nucleated cells in BM -NC ratio 3-5:1 -fine chromatin, slight clumping 1-3 nucleoli -blue cytoplasm, primary azurophilic granules -Granules filled w myeloperoxidase, has affinity for azure dye in wright stain
1.1.1 Myelocyte

Annotations:

  • -10% of circulating cells in BM -NC ratio 1-2:1 round to oval cell -nuclues oval to slightly indented/flattenned, chromatin clumping and no nucleoli visible -primary and 2ndary specific neutrophilic granules -LAST STAGE CAPABLE OF MITOSIS
1.1.1.1 Metamyelocyte

Annotations:

  • -nucleus begins to indent, chromatin more clumped -10 to 15 um -IMPORTANCE OF STAGE: makes super O2 imp in killing microbes!
  • STAB OR BAND FORM -nucleus indents forming U shape parralel on both sides -2/3 of granules are 2ndry -5-10% in norm PB
1.1.1.1.1 Segmented Neutrophil

Annotations:

  • -2-4 lobes connected by thin fillament
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