Renal system (2)

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100-level Human Bioscience: Normal Body Function (Module 5) Mind Map on Renal system (2), created by Antonia Smith on 18/01/2016.
Antonia Smith
Mind Map by Antonia Smith, updated more than 1 year ago
Antonia Smith
Created by Antonia Smith over 8 years ago
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Resource summary

Renal system (2)
  1. Explain net filtration pressure
    1. Blood hydrostatic pressure entering the renal corpuscle is 55mmHg, an appropriate pressure for filtration, but it is conflicted by other pressures. The pressure of the glomerular capsule against the capillary is 15mmHg, and the blood colloid osmotic pressure created by proteins in the blood drawing some filtrate back through the fenestrations is 30mmHg. This leaves the net filtration pressure at 10mmHg, which is sufficient, but is part of why it is important that the kidneys help keep blood pressure regulated.
    2. Explain the function of the kidney in maintaining blood pressure
      1. Low BP - Renin released from kidney
        1. Renin converts angiotensinogen in blood to angiotensin - causes vasoconstriction
          1. Angiotensin triggers aldosterone release from adrenal gland
            1. Aldosterone causes increased Na+ reabsorption
              1. Higher Na+ (osmolality) causes increased water reabsorption
                1. = Higher blood volume, regulated BP
            2. Vasoconstriction = increased BP
        2. Explain the micturition (expulsion of urine) reflex
          1. Involuntary reflex i.e. babies pee when urge arises
            1. Ability to decide to override reflex is learnt
              1. Bladder fills
                1. Stretch receptors are fired
                  1. Made aware of need to urinate
                    1. Internal involuntary sphincter relaxes
                      1. For urination, the external voluntary sphincter must relax
                        1. If not ok to urinate, internal involuntary sphincter contracts & bladder relaxes
                          1. However, stimulus (urine) still present, so stretch receptors will fire again until micturition is possible (if ability to decide is developed)
              2. Describe effects of aging on the urinary system
                1. Nephrons reduced to 1/3 of original amount with old age so are not as efficient
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