Flashcards
C.tetani
Flashcards do conjunto (11)
- 1Disease CausedTetanus
- 2Source of BacteriaDust/soil in wounds
- 3Aerobic or Anaerobic?All Clostridium are Obligate Anaerobes
- 4Tetanospasmin (Exotoxin) Structure2 heavy chains, 1 light chain
- 5Tetanospasmin (Exotoxin) Role of Structure2 heavy chains- bind to nerve terminal, light chain causes effect
- 6Tetanospasmin (Exotoxin) BindingTo gangliosidase Receptors, which endocytose it and release it in the CNS
- 7Tetanospasmin (Exotoxin) Inhibitory NeuronesTaken up by 'muscle relaxing' neurones, where light chain binds snare protein Synaptoprenin
- 8Tetanospasmin (Exotoxin) EffectNeurotransmitter cannot be release, muscles cannot relax
- 9SymptomsLockjaw, arched spin, bent limbs, respiratory spasm
- 10VaccineDirected against tetanospasmin
- 11AtoxoidInactive toxin that triggers the immune system (found in vaccine)
Informações
- Descrição
- Medical Microbiology (Clostridium Family) FlashCards sobre C.tetani, criado por gina_evans0312 em 03-04-2014.
- Criado por
- gina_evans0312
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