Questão 1
Questão
The most frequent form of primary glomerular disease in children is
Responda
-
Minimal change disease
-
Acute glomeruonephritis
Questão 2
Questão
Hyperfunction of anterior pituitary in pre-pubertal children generally can result in
Questão 3
Questão
The role of external radiation in the etiology of thyroid cancer is predominant in
Responda
-
Papillary carcinoma
-
Follicular carcinoma
Questão 4
Questão
The following type of carcinoma of the breast is characterised by 'Indian file' pattern of tumour cells
Questão 5
Questão
Prostatic hyperplasia affects most often
Responda
-
Peripheral prostate
-
Periurethral prostate
Questão 6
Questão
Which criteria refer to pernicious anaemia
Questão 7
Questão
Which of the following tumours have association with occupational exposure to asbestosis?
Responda
-
Silicosis
-
Malignant mesothelioma
-
Squamous cell carcinoma
-
Laryngeal carcinoma
Questão 8
Questão
Which of the following features characterise ulcerative colitis, except
Responda
-
Formation of crypt abscess and cryptitis
-
Superficial mucosal ulceration
-
Depletion of goblet cells and mucus
-
Stricture formation in chronic cases
Questão 9
Questão
Philadelphia chromosome is characterised by
Responda
-
Translocation (8;14)
-
Translocation (9;22)
-
Translocation (22;9)
-
Translocation (14;8)
Questão 10
Questão
Which of the following are included in classic Hodgkin's disease
Responda
-
Histiocytic fibrosis
-
Lymphocytic depletion
-
Mixed cellularity
-
Nodular sclerosis
Questão 11
Questão
Pulseless disease is
Responda
-
Temporal arteritis
-
Kawasaki's disease
-
Takayasu arteritis
-
Buerger's disease
Questão 12
Questão
The morphological variants of diagnostic cells in Hodgkin's disease are
Questão 13
Questão
Crohn's disease is characterised by the following histopathologic features
Questão 14
Questão
According to monoclonal atherosclerosis hypothesis, the primary event in atherosclerosis is
Responda
-
Monoclonal proliferation of endothelial cells
-
Monoclonal proliferation of smooth muscle cells
-
Monoclonal proliferation of monocytes
-
Monoclonal proliferation of foam cells
Questão 15
Questão
Barrett's oesophagus is
Responda
-
Congenital anomaly
-
Inflammatory disease
-
Metaplastic process
-
Neoplastic lesion
Questão 16
Questão
The most common site of involvement of atherosclerosis aneurysm is
Questão 17
Questão
The following histologic types of bronchogenic carcinoma have strong association with cigarette smoking except
Responda
-
Squamous cell carcinoma
-
Small cell carcinoma
-
Large cell carcinoma
-
Adenocarcinoma
Questão 18
Questão
The most important and common complicated atheromatous lesion in the coronary artery in acute myocardial infarction is
Questão 19
Questão
In hypertensive heart disease left ventricular hypertrophy is correlated with
Questão 20
Questão
The most common causative agent for lobar pneumonia is
Responda
-
Staphylococci
-
Streptococci
-
Pneumococci
-
Haemophilus
Questão 21
Questão
The common complications of gastric ulcer are
Responda
-
Penetration
-
Pneumonia
-
Haemorrhage
-
Perforation
Questão 22
Questão
What complication can occur due to atherosclerosis of femoral artery?
Questão 23
Questão
Which of the following types of acute viral hepatitis become chronic hepatitis?
Questão 24
Questão
Nephrotic syndrome develops in
Responda
-
Urine retention
-
Acute renal failure
-
Acute pyelonephritis
-
Glomerulonephritis
Questão 25
Questão
The infection which leads to pyelonephritis may be a result of
Questão 26
Questão
Which of the following diseases does not lead to nephrosclerosis?
Responda
-
Atherosclerosis
-
Diabetes mellitus
-
Diabetes insipidus
-
Gout
Questão 27
Questão
Squamous cell carcinoma is a common tumour in the
Responda
-
Uterine body
-
Ovaries
-
Fallopian tubes
-
Uterine cervix
Questão 28
Questão
Which of the morphological methods are used for subtyping lymphomas?
Responda
-
Van Gieson staining
-
PAS
-
Von Kossa staining
-
Immunohistochemistry
Questão 29
Questão
Which of the following complications can develop in pulmonary carcinoma?
Questão 30
Questão
Determine the pathological process in the lung emphysema, having in mind the microscopic appearance - a focus of necrosis, detritus, leukocytes and macrophages
Questão 31
Questão
What disease is endometriosis?
Questão 32
Questão
Point out the characteristic macroscopic changes of chronic obstructive emphysema
Responda
-
Decreased in size lungs, collapsed to the hilum
-
Lungs with increased volume
-
Thick consistency of the lungs
-
Reduced elasticity and soft consistency
Questão 33
Questão
Gynecomastia is a disease of
Responda
-
Breast in women
-
Ovaries
-
Male breast
-
Testes
Questão 34
Questão
What is typical for the first stage of syphilis?
Questão 35
Questão
For tuberculous meningitis the following histological changes are typical
Questão 36
Questão
Why are occupational diseases named pneumoconiosis?
Questão 37
Questão
Which of the following factors play a role in the development of bronchial carcinoma?
Questão 38
Questão
What is the exudate in the pleural cavity and pericardial sac due to lymphatic spread of pulmonary carcinoma into them?
Responda
-
Fibrinous
-
Serious
-
Haemorrhagic
-
Purulent
Questão 39
Questão
What forms of silicosis do you know?
Questão 40
Questão
Apically located peripheral pulmonary carcinoma is represented by the eponym
Questão 41
Questão
Which diseases complicate silicosis?
Responda
-
Cor hypertonicum
-
Cor pulmonale chronicum
-
Tuberculosis
-
Pneumofibrosis
Questão 42
Questão
Claude-Bernard-Horner syndrome includes the following
Responda
-
Ptosis, midriasis, anhydrosis
-
Ptosis, miosis, increased sweating
-
Ptosis, miosis, pseudoenophthalmus
-
Anhydrosis
Questão 43
Questão
What possible gross changes do we see in lung carcinoma?
Questão 44
Questão
Chronic bronchitis is usually accompanied by
Responda
-
Squamous cell metaplasia of the respiratory epithelium
-
Phases of purulent inflammation
-
Productive cough for at least 2 months/year for 3 consecutive years
-
Productive cough for at least 3 months/year for 2 consecutive years
Questão 45
Questão
Squamous cell lung carcinoma occurs
Responda
-
In the middle lobe of the left lung
-
After squamous cell metaplasia of the respiratory epithelium of bronchi
-
As an ill-defined node connected to a bronchus
-
Forming nests of Tumour cells producing keratin
Questão 46
Questão
In small cell lung carcinoma we can observe
Responda
-
Numerous Tumour cells with scant stroma
-
The tumour cells resemble oat-grains
-
It grows in a pneumonia-like fashion
-
The tumour cells have very high proliferative rate
Questão 47
Questão
Bronchio-alveolar pulmonary carcinoma is characterised by
Responda
-
Forms papillary folds into the alveolar lumen
-
It is a form of squamous cell carcinoma
-
The cells produce keratin
-
It is a form of adenocarcinoma
Questão 48
Questão
Hodgkin lymphoma has
Questão 49
Questão
In Hodgkin lymphoma we can observe
Responda
-
Effaced lymph node structure
-
Nodular sclerosis histological form
-
Mixed cellularity histological form
-
Chronic myeloleukemia
Questão 50
Questão
Non-Hodgkin lymphomas can be
Responda
-
Nodal
-
B-cell and T-cell types
-
Extranodal
-
None of the above
Questão 51
Questão
In chronic lympholeukemia in the liver can be seen
Responda
-
Myeloblasts
-
Mature lymphocytes and single lymphoblasts
-
Focal leukemic infiltrates in the portal spaces
-
Leukemic infiltrates in the sinusoids
Questão 52
Questão
Chronic myeloleukemia causes the following changes in liver
Responda
-
Effaced lobular structure
-
Hypertrophy and hyperplasia of hepatocytes
-
Atrophy of hepatocytes
-
Leukaemic infiltrates in the sinusoids
Questão 53
Questão
In chronic myeloleukemia we observe the following
Responda
-
Long remissions even without treatment
-
Extreme hepato-splenomegaly
-
Anemia, hemorrhages, infections
-
Splenic infarctions
Questão 54
Questão
Which are the clinical phases of chronic myeloleukemia?
Responda
-
Chronic stable phase
-
Accelerated phase
-
Blast crisis
-
None of the above
Questão 55
Questão
In Hodgkin lymphoma, mixed cellularity type
Responda
-
There can be seen numerous eosinophils
-
We can observe area with necrosis
-
Intact histological lymph nose structure
-
Giant bi-uncleared cells, called 'mirror image'
Questão 56
Questão
Plasmocytoma has the following features
Responda
-
Reed-Sternberg Tumour cells
-
Jelly-like raspberry red osteolytic bone lesion
-
The tumour cells have a large vacuolar nucleus with prominent nucleolus
-
The tumour cells have a round eccentric nucleus with a pale halo around it
Questão 57
Questão
Which of the following are examples of pathological processes in the oral cavity that can have an effect of internal organs?
Questão 58
Questão
Which avitaminoses can be associated with changes in the oral cavity?
Responda
-
Vit. B6
-
Vit. B12
-
Vit. D
-
None of the above
Questão 59
Questão
Vitamin B12 deficiency can cause the following changes in the oral cavity
Questão 60
Questão
What type of examination will you suggest to your patient if you diagnose him/her with atrophic glossitis (Hunter's tongue)?
Responda
-
Colonoscopy
-
Dermatoscopy
-
Gastroscopy
-
Hysteroscopy
Questão 61
Questão
If a patient with atrophic glossitis is examined with gastroscopy, what can be the findings in gastric mucosa?
Questão 62
Questão
The risk of which disease does atrophic autoimmune gastritis carry?
Questão 63
Questão
What are the usual changes in leukoplakia?
Responda
-
The epithelium is hyperkeratotic
-
Acanthosis in the epithelium
-
Chronic inflammation
-
Dysplasia in the epithelium can be observed
Questão 64
Questão
What can we observe in leukoplakia?
Responda
-
Parakeratosis
-
Dysplasia
-
Carcinoma in situ
-
Diabetes
Questão 65
Questão
Which of the following is true of pleomorphic adenoma of the parotid gland
Questão 66
Questão
In chronic tonsillitis we can observe the following
Questão 67
Questão
The typical histological picture of epilus includes
Responda
-
Langhans giant multinuclear cells
-
Fresh haemorrhages and hemosiderin
-
Osteoclast-type multinuclear giant cells
-
It is a true tumour
Questão 68
Questão
Adamantinoma (amelloblastoma) is
Questão 69
Questão
Why is it necessary to comment on the presence or absence of H.pylori in gastric biopsies?
Responda
-
H.pylori is a risk factor for MALT lymphoma
-
H.pylori is a risk factor for duodenal cancer
-
H.pylori causes chronic gastritis
-
H.pylori is a severe fungal infection
Questão 70
Questão
Which of the following are possible complications of chronic gastric ulcer?
Questão 71
Questão
Which special stain help us determine the presence of H.pylori in gastric biopsies?
Responda
-
Van Gieson
-
Giemsa
-
Congo Red
-
Immunohistochemistry
Questão 72
Questão
The following changes can be observed in acute duodenal ulcer
Responda
-
Fibrinoid necrosis at the ulcer base
-
Inflammatory infiltrate with lymphocytes and plasma cells
-
Ulceration penetrating through muscularis mucosae, reaching muscularis propria
-
It often undergoes malignant transformation
Questão 73
Questão
What histological types of gastric cancer do you recognise?
Questão 74
Questão
In phlegmonous appendicitis we can observe the following
Responda
-
Peri-appendicitis
-
Lymphocyte infiltration in the mucosa
-
Neutrophilic infiltration throughout the thickness of the wall of the appendix
-
Constriction of the blood vessels of the serosa
Questão 75
Questão
Phlegmonous appendicitis is characterised by
Responda
-
Purulent exudate in the lumen
-
Hypoplasia of the lymph follicles
-
Hyperplastic activated lymph follicles
-
Hyperemic blood vessels of the serosa
Questão 76
Questão
Gangrenous appendicitis is characterised by
Responda
-
Lymphocytic infiltration of the mucosa
-
Thrombosis of blood vessels
-
Necrosis of the wall of the appendix
-
Severe inflammation through the wall of the appendix
Questão 77
Questão
What are the causes which may lead to micro-nodular liver cirrhosis?
Responda
-
Acute viral hepatitis
-
Chronic viral hepatitis
-
Cardiogenic shock
-
Chronic alcoholism
Questão 78
Questão
Which of the types of necrosis are found in chronic active hepatitis?
Responda
-
Piece-meal necrosis
-
Adjacent necrosis
-
Bridging necrosis
-
Caseous necrosis
Questão 79
Questão
Why does the level of calcium in the blood has prognostic value in acute pancreatitis?
Responda
-
Calcium is deposited in the bones
-
Calcium levels in the blood slower with the progression of steato-necrosis
-
Calcium reacts with fatty acids to form soaps
-
It has no prognostic value
Questão 80
Questão
Some of the gross features of acute pancreatitis are
Responda
-
Enlarged liver
-
Steatonecrosis of the fatty tissue around and inside the pancreas
-
Haemorrhages in the tissues of the pancreas
-
Fibrosis in the tissues of the pancreas
Questão 81
Questão
What histological changes can be observed in chronic hepatitis?
Questão 82
Questão
Chronic cholecystitis is characterised by the following
Responda
-
Often it is accompanied by cholelithiasis
-
It has no association with cholelithiasis
-
Can cause adhesions
-
It is caused by viral infection
Questão 83
Questão
Which is the following can be complications caused by chronic cholecystitis?
Questão 84
Questão
After consuming poisonous mushrooms, a patient shows signs of acute liver failure with progressive reduction of the size of the liver. What process has developed in the liver?
Responda
-
Acute viral hepatitis
-
Massive hepatic necrosis
-
Hepatocellular carcinoma
-
None of the above
Questão 85
Questão
After consuming poisonous mushrooms, a patient shows signs of acute liver failure with progressive reduction of the size of the liver. Besides liver failure, what other complication can worsen the patient's clinical condition?
Questão 86
Questão
Which of the following can occur after a streptococcal tonsillitis?
Responda
-
Post-infectious cholecystitis
-
Post-infectious glomerulonephritis
-
Minimal change disease of the kidneys
-
Acute rheumatism
Questão 87
Questão
Which types of glomerulonephritis are clinically presented by nephritic syndrome?
Responda
-
Diffuse endocapillary glomerulonephritis
-
Rapidly progressing glomerulonephritis
-
Minimal change disease
-
Membranous glomerulonephritis
Questão 88
Questão
Which types of glomerulonephritis are clinically presented by nephrotic syndrome?
Responda
-
Diffuse endocapillary glomerulonephritis
-
Rapidly progressing glomerulonephritis
-
Minimal change disease
-
Membranous glomerulonephritis
Questão 89
Questão
What findings can be observed in glomerulonephritis?
Responda
-
Klebsiella
-
E.coli
-
Streptococcus
-
The urine is sterile
Questão 90
Questão
Which type of glomerulonephritis is 'crescentic'?
Responda
-
Minimal change disease
-
Rapidly progressing glomerulonephritis
-
Membranous glomerulonephritis
-
Diffuse endocapillary glomerulonephritis
Questão 91
Questão
'Big white kidney' can be observed in the following cades
Responda
-
Rapidly progressing glomerulonephritis
-
Amyloidosis of the kidney
-
Minimal change disease
-
Nephrosclerotic glomerulonephritis
Questão 92
Questão
Which of the following histological changes are associated with tubal pregnancy?
Responda
-
Chorionic Villi and decidual Changes of the endometrium
-
Monstrous trophoblast, hydropic chorionic villi
-
Hematoma in Fallopian tube, chorionic villi invading the muscular layer of the tube, decidual changes of the endometrium
-
Cervical intraepithelial lesion, third grade
Questão 93
Questão
Which of the following histological changes are associated with mola hydatidosa?
Responda
-
Chorionic Villi and decidual Changes of the endometrium
-
Monstrous trophoblast, hydropic chorionic villi without feral blood capillaries
-
Hematoma in Fallopian tube, chorionic villi invading the muscular layer of the tube, decidual changes of the endometrium
-
Cervical intraepithelial lesion, third grade
Questão 94
Questão
Which of the following histological changes are associated with abortion (miscarriage) ?
Responda
-
Chorionic Villi and decidual Changes of the endometrium
-
Monstrous trophoblast, hydropic chorionic villi without feral blood capillaries
-
Hematoma in Fallopian tube, chorionic villi invading the muscular layer of the tube, decidual changes of the endometrium
-
Cervical intraepithelial lesion, third grade
Questão 95
Questão
Specify the associated clinical symptoms in dysplasia and carcinoma in situ of the uterine cervix
Questão 96
Questão
Why if curettage from a suspected pregnancy shows only decidual changes, the gynaecologist should be notified immediately?
Responda
-
There is an increased risk for endometrial carcinoma
-
There is an increased risk of associated mola hydatidosa
-
There is an increased risk of associated intraepithelial lesion of the cervix
-
There is a high risk of associated tubal pregnancy
Questão 97
Questão
Mola hydatidosa has the following characteristics
Responda
-
Grossly it resembles grape-like structures
-
Chorionic villi have fetal capillaries
-
Chorionic villi are with hydropic edema
-
Chorionic villi lack fetal blood vessels
Questão 98
Questão
Examples of ovarian cysts are
Questão 99
Questão
Which hormones play a role in breast diseases?
Responda
-
Somatropin
-
Oxytocin
-
Estrogen
-
Progesterone
Questão 100
Questão
How does the breast cancer metastasise?