Pharmacology Vet 202 Chapter Nine Study Guide

The drug of choice for managing seizures long term is an oral barbiturate that has the benefit of being relatively inexpensive while having an extensive half-life. What is this drug?

Over time, barbiturate use results in upregulation of the enzymes responsible for the drug’s breakdown. This phenomenon is known as enzyme __________________.

Diazepam is a benzodiazepine tranquilizer that, in contrast to phenobarbital which is used as a long-term anti-seizure medication, is instead used as an emergency IV drug for use during an active convulsion. All of the following are characteristics of diazepam except one. Which choice is incorrect?

Which of the following is a property of potassium bromide?

There are several mechanisms of action for behavior-modifying drugs used in veterinary medicine. Which of the following is not considered one of these mechanisms?

Which neurotransmitter does acepromazine antagonize to decrease anxiety in both humans and veterinary patients?

Which of the following classes of antidepressant medications function by modifying the activity of enzymes that are responsible for the biotransformation of neurotransmitters?

What is the general role of the neurotransmitter serotonin?

What is primidone’s primary mechanism of activity?

An uncommonly used unit of measurement that is often used in conjunction with barbiturates is the grain. What is the size in milligrams of a 2-grain phenobarbital tablet?

Seizures generally originate from the brain but seizure activity can also arise from other causes. Veterinary technicians should always consider these other sources except:

________________ is the term used to describe seizure activity that is prolonged and can result in positive feedback where muscle activity increases temperature and increase seizure activity.

Phenobarbital used to control seizures has a well-established therapeutic range for dogs but dosages vary widely based upon:

Side effects of using phenobarbital to control seizure activity in dogs include

Phenobarbital induced hepatotoxicity:

On an animal that is not responding particularly well to phenobarbital or the phenobarbital/bromide combination for long-term seizure control, all of the following drugs might be tried except:

Drugs that “lyse” anxiety or decrease fear responses are called:

Three classes of antidepressant drugs used in human beings have also found use in veterinary medicine include all except:

Clomipramine’s FDA–approved indication is for treatment of obsessive-compulsive disorders in dogs. A more common use of clomipramine in veterinary medicine is for:

Plasma phenobarbital concentrations achieved with any given dose vary considerably from patient to patient. Therefore, the only way to ensure a dosage regimen is adequate is to

When considering neurotransmitter-modifying drugs for behavior therapy, which of the following is true?

Potassium bromide is used as an adjunct drug for treating seizures when standard doses of barbiturates prove ineffective alone. Considering the long 3-week half-life of potassium bromide, how would you determine the length of time it takes to reach a steady state when using this drug daily?

Which of the following is not a side effect of barbiturate use?

What is the portion of the brain that controls animal emotion and is thus targeted for alteration by behavior-modifying drugs?

In addition to treating behavioral problems, selegiline is also used to treat this condition in dogs.