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Mechanisms of Cell injury

Kayleigh Van 12 Fragen

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  1. 1Terminology:
    1. [blank_start]aetiology[blank_end]: cause of disease
    2. [blank_start]pathogenesis[blank_end]: the mechanism of how disease develops
    3. [blank_start]morphological changes[blank_end]: structural changes in tissues and organs
    4. [blank_start]clinical significance[blank_end]: functional consequences
    5. [blank_start]antemortem[blank_end]: before death
    6. [blank_start]postmortem[blank_end]: after death
    7. [blank_start]anatomical pathology[blank_end]: postmortem and tissue biopsy
    8. [blank_start]gross pathology[blank_end]: postmortem with naked eye
    9. [blank_start]histopathology[blank_end]: postmortem with microscope
    10. [blank_start]clinical pathology[blank_end]: analysis of body fluids and cells
    1. Aaetiology
    2. Bpathogenesis
    3. Cmorphological changes
    4. Dclinical significance
    5. Eantemortem
    6. Fpostmortem
    7. Ganatomical pathology
    8. Hgross pathology
    9. Ihistopathology
    10. Jclinical pathology
  2. 2ATP depletion is caused by [blank_start]hypoxia[blank_end] resulting in [blank_start]decreased[blank_end] oxidative posphorylation, [blank_start]decreased[blank_end] ATP, [blank_start]increased[blank_end] anaerobic glycolysis, [blank_start]decreased[blank_end] glycogen and decreased pH. the sodium potassium pump fails and ribosomes [blank_start]detach from[blank_end] the RER.
    1. Ahypoxia
    2. Bfree radicals
    3. Cdecreased
    4. Dincreased
    5. Edecreased
    6. Fincreased
    7. Gincreased
    8. Hdecreased
    9. Idecreased
    10. Jincreased
    11. Kdetach from
    12. Lattach to
  3. 3the three main causes of membrane damage are:
    1. [blank_start]free radicals[blank_end] that cause lipid peroxidation
    2. [blank_start]direct damage[blank_end] from chemicals, viruses etc.
    3. [blank_start]Hypoxia[blank_end] resulting in ATP depletion.
    1. Afree radicals
    2. Bdirect damage
    3. CHypoxia
  4. 4the most reactive oxygen species are [blank_start]superoxide[blank_end], [blank_start]hydrogen peroxide[blank_end] and [blank_start]hydroxyl radical[blank_end].
    1. Asuperoxide
    2. Bhydrogen peroxide
    3. Chydroxyl radical
  5. 5which of the following are sources of free radicals?
    1. Aby-products of oxidative metabolism
    2. Bphagocytic cells
    3. Cmetals
    4. Dorganophosphates
    5. Ereperfusion following necrosis
    6. Freperfusion following ischaemia
    7. Gradiation and UV light
    8. Hdrug and chemical exposure
    9. Initric oxide.
  6. 6free radicals injure cells via:
    1. [blank_start]lipid peroxidation[blank_end] leading to extensive membrane damage
    2. [blank_start]DNA damage[blank_end] which causes sing strand breaks
    3. [blank_start]protein damage[blank_end] which causes the oxidation of amino acids
    1. Alipid peroxidation
    2. BDNA damage
    3. Cprotein damage
  7. 7two patterns of reversible cell injury include:
    1. [blank_start]hydropic degeneration[blank_end]: acute cell swelling due to fluid influx
    2. [blank_start]fatty change[blank_end]: cell swelling due to lipid accumulation
    1. Ahydropic degeneration
    2. Bfatty change
  8. 8increased cytosolic calcium is associated with reversible cell injury.
    1. ARichtig
    2. BFalsch
  9. 9what type of cell injury is seen here microscopically? is it reversible?Bild zu Frage 9
    1. Afatty change
    2. Bhydropic degeneration
    3. Cno it is not reversible
    4. Dyes it is reversible
  10. 10what type of cell injury is seen here grossly? is it reversible?Bild zu Frage 10
    1. Afatty change
    2. Bhydropic degeneration
    3. Cno it is not reversible
    4. Dyes it is reversible

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Beschreibung
Pathology (Introductory principles) Quiz am Mechanisms of Cell injury, erstellt von Kayleigh Van am 19/10/2016.
Sprache
English
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