Flashcards
Rhodococcus
Cards in this deck (15)
- 1What is the microscopic appearance of Rhodococcus?Gram +, pleomorphic, non-motile
- 2How to detect Rhodococcus?PCR and cytology. If false negative, thoracic radiographs are helpful for diagnosis.
- 3What tests do we do for identification of Rhodococcus? One is specific for R..equi:Cat +
Ox -
Gram +
CAMP test - 4What is the principle of CAMP test?R.equi produces phospholipases that enhance the hemolytic activity of S.aureus B toxin.
- 5What do you know on Rhodococcus resistance and sensitivity?RESISTANT- to acid (phaagolysosomes), UV light, desiccation= persists in eq. environment. To β lactams and TE
SENSITIVE- to most Abs for G+ - 6Is rhodococcus resistant to penicillin?Yes
- 7What is one property that protects R.Equi from the immune system of the host? (similar to M.tuberculosis)1) prevents fusion of phagosome and lysosome
2) Inhibits respiratory burst.
These allow R.equi to multiply within the phagosome shielded by the immune system. Survives in macrophages - 8Which strain of Rhodococcus affects plants?R.fascians- phytopathogen- leafy gall disease.
- 9What species are hosts to R.equi?Pigs- In lymph nodes
Goats and Cattle- RARE
Humans- if immunosup. pulmonary inf.
HORSES- bronchopneumonia in foals - 10What is the result of R.equi infection in horses?Infection of macrophages in lungs where it replicates and damage the surrounding tissue. Leaves host w/ immunosuppression towards other respiratory infections.
- 11How is R.equi transmitted?By ingestion or inhalation. Mostly in summer when manure is dry-- aerosolization= inhale
- 12What important factor does Rhodococcus have that is the cause of infections?85-90kb Virulence plasmid. Bacteria lacking this plasmid are non-infectious.
- 13What other virulence factors does it have?LAM- lipos-arbaino-mannan: cell envelope lipid. Also cell wall lipids that affect recognition by the immune system of host within CD1-T cell.
- 14what is the result of rhodococcus infection in goats?Hepatic abscesses but rare
- 15What samples are used for testing?Trans-Tracheal washes
Information
- Description
- Microbiology Flashcards on Rhodococcus, created by Sotia P. on 22/04/2019.
- Created by
- Sotia P.
- Views
- 5
- Tags
- Rating