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Acid-Base Balance

Lareyna Mcmenemy MD3001 Inglés 17 fichas

Acid-Base Balance

Fichas del conjunto (17)

  1. 1What is a normal blood pH?7.4
  2. 2How do you calculate blood pH from given values?pH = pKa + log [HCO3-]/[CO2]
  3. 3What are the axis of a Davenport diagram?Y-axis = Plasma HCO3- concentration
    X-axis = Plasma pH
  4. 4How will a Davenport diagram differ with change to PCO2 or change in non-volatile acid or baes?How will a Davenport diagram differ with change to PCO2 or change in non-volatile acid or baes?
  5. 5List the primary causes of acid-base disturbancesIncreased or decreased CO2
    Increased or decreased non-volatile acid
    Increased or decreased to non-volatile base
  6. 6What are the pH values for acidosis & alkalosis?pH of <7.35 = Acidosis
    pH of >7.45 = Alkalosis
  7. 7Describe, with the use of a Davenport diagram, respiratory acidosisRespiratory acidosis results form a rise in PCO2 or fall in HCO3-Describe, with the use of a Davenport diagram, respiratory acidosis
  8. 8How is respiratory acidosis compensated for?Renal compensation
    - increased HCO3- secretion from the kidneys raises pH back to normal as equilibrium shifts to the left
    Note... opposite is true for respiratory alkalosis
  9. 9What are the main causes of respiratory acidosis?COPD
    Blockage of airways
    Lung collapse
    Chest wall injury
    Drugs which reduce respiratory drive
  10. 10Describe, with the use of a Davenport diagram, respiratory alkalosisRespiratory alkalosis results from a decrease in PCO2Describe, with the use of a Davenport diagram, respiratory alkalosis
  11. 11What causes respiratory alkalosis?Hyperventilation
    Increased ventilation from hypoxic drive - pneumonia, diffuse interstitial lung disease, high altitude etc.
  12. 12Describe, with the use of a Davenport diagram, metabolic acidosisMetabolic acidosis results from an increase in H+ resulting in a decrease in HCO3-Describe, with the use of a Davenport diagram, metabolic acidosis
  13. 13How is metabolic acidosis compensated for?Respiratory compensation
    - lower pH is detected by peripheral chemoreceptors causing an increase in ventilation to lower PCO2
    - slow renal compensation is also required to remove excess H+ or restore HCO3-
  14. 14What causes metabolic acidosis?Loss of HCO3- e.g. diarrhoea
    Exogenous acid overdose eg. aspirin
    Ketogenesis
    Renal failure
  15. 15Describe, with the use of a Davenport diagram, metabolic alkalosisMetabolic alkalosis results from an increase in HCO3- or fall in H+Describe, with the use of a Davenport diagram, metabolic alkalosis
  16. 16How is metabolic alkalosis compensated for?Increased pH is detected by peripheral chemoreceptors, which decrease ventilation to increased PCO2
    - small renal response to produce for H+
  17. 17What causes metabolic alkalosis?Vomiting - loss of HCL
    Ingestion of alkali substances
    Potassium depletion e.g. diuretic use

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(Respiratory System) MD3001 Fichas sobre Acid-Base Balance, creado por Lareyna Mcmenemy el 03/12/2018.
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