Test
Alpha 1 Adrenergic Receptor Pathway
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Preguntas del test (15)
1Which Gprotein causes the activation Phospholipase CBeta?
- AGq
- BGs
- CGi
2How is Phospholipase CBeta activated?
- ABy GTP binding to the alpha subunit of the Gq protein
- BBy ATP binding to the alpha subunit of the Gq protein
- CBy GMP binding to the alpha subunit of the Gq protein
3What is broken down by phospholipase CBeta?
- APhosphatidynositol 4,5 bisphophate
- BPhosphatidynositol 3,5 bisphophate
- CPhosphatidynositol 2,4 bisphophate
4Which product of the PCbeta pathway causes the release of calcium from the ER?
- AIP3
- BDiacylglycerol
5What role(s) does the released Ca perform?
- AActivates protein kinase C
- BActivates protein kinase B
- CActivates various Ca dependent protein kinases
6What residues are phosphorylated by the protein kinases activated by this pathway?
- ASerine
- BThreonine
- CTyrosine
7Which subunit of Protein Kinase C contains the pseudosubstrate domain?
- APS
- BC1A
- CC4
8What is the function of subunut C1A
- ADAG binding site
- BCalcium binding site
- CPhosphatidyl serine binding site
9Do Ca 2+ and phosphatidyl serine bind to subunit C2?
- AYes
- BNo
10Which subunits are part of the catalytic domain?
- AC1A
- BC3
- CC4
- DPS
- EC5
11ATP binds to C2, True or False?
- ATrue
- BFalse
12When IP3 causes the increase in cytosolic calcium, what happens to protein kinase C?
- AIt moves to the membrane and binds with DAG
- BIt remains in the cytoplasm and binds with DAG
13Once protein kinase C has bound to DAG in the membrane, what does it then bind to to release the pseudosubstrate from its active site?
- APhosphatidylserine
- BPhosphatidylglycine
- CPhosphatidylglutamate
14Which of the following is a tumor promoting agent?
- APhorbol ester
- BOrphol ester
- CPhenyl ester
15How do tumor promoting agents effect Phospholipase CBeta?
- AThey bind without being degraded, so it becomes hyperactive
- BThey stop the alpha subunit binding, so it becomes unreactive
- CThey cause the multiplication of the number of PCbeta enzymes in the cell, causing hyperactivity
Información
- Descripción
- Year 2 Test sobre Alpha 1 Adrenergic Receptor Pathway, creado por gina_evans0312 el 03/11/2013.
- Autor
- gina_evans0312
- Idioma
- English
- Visitas
- 633
- Etiquetas
- Valoración
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