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Description
Flashcards by Evian Chai, updated more than 1 year ago
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Created by Evian Chai
about 4 years ago
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| Question | Answer |
| How does Hemicholiniums block cholinergic transmission? | Blocks the synthesis of ACh |
| How does AH5283 block cholinergic transmission? | Prevents storage of ACh |
| Cholinergic neurotransmission uses what neurotransmitter? | Acetylcholine |
| How does botox block cholinergic neurotransmission? | Blocks exocytosis of ACh |
| What type of receptors are nicotinic receptors? | Non selective cation channels |
| What are the two types of nicotinic drugs? | 1. Skeletal muscle relaxants (antagonist) 2. Ganglion blockers (antagonist, lower BP) |
| Are skeletal muscle relaxants agonists or antagonists? Reversible or Irreversible? Competitive or Non-competitive? | They are reversible competitive antagonists |
| What do muscarinic agonists do? | Mimic the PNS |
| Which drug treats glaucoma by increasing aqueous humour flow? What kind of drug is this? | Pilocarpine Muscarinic agonist |
| What drug is a stimulant laxative? What kind of drug is this? | Bethanacol Muscarinic agonist |
| What do muscarinic antagonists do? What are their effects on the pupils? | Inhibit the PNS Pupil dilation |
| What drug is used to treat sinus bradycardia? What type of drug is this? | Atropine Muscarinic antagonist |
| Both muscarinic antagonists and B2 agonists can treat what? | Asthma, as they block PNS/increase SNS effects eg. bronchodilation |
| What do Inhibitors of Acetylcholinesterase do? What does it do for the PNS? | Prevent the breakdown of acetylcholine to increase neurotransmission Increases PNS activity eg. secretions, SM tone, hypotension, bradycardia |
| Which drug reverses skeletal muscle relaxants? What type of drug is this? | Neostigmine AChE inhibitor |
| What inhibitor of AchE aids Alzheimers? | Donepezil |
| What are the 5 main types of drugs impacting cholinergic transmission? | 1. Skeletal muscle relaxants (cholinergic) 2. Ganglion blockers (cholinergic) 3. Muscarinic agonists 4. Muscarinic antagonists 5. Inhibitors of AchE |
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