Flashcards
BMS03-1023 Pharmacology of Cholinergic Transmissions
Cards in this deck (17)
- 1How does Hemicholiniums block cholinergic transmission?Blocks the synthesis of ACh
- 2How does AH5283 block cholinergic transmission?Prevents storage of ACh
- 3Cholinergic neurotransmission uses what neurotransmitter?Acetylcholine
- 4How does botox block cholinergic neurotransmission?Blocks exocytosis of ACh
- 5What type of receptors are nicotinic receptors?Non selective cation channels
- 6What are the two types of nicotinic drugs?1. Skeletal muscle relaxants (antagonist)
2. Ganglion blockers (antagonist, lower BP) - 7Are skeletal muscle relaxants agonists or antagonists? Reversible or Irreversible? Competitive or Non-competitive?They are reversible competitive antagonists
- 8What do muscarinic agonists do?Mimic the PNS
- 9Which drug treats glaucoma by increasing aqueous humour flow? What kind of drug is this?Pilocarpine
Muscarinic agonist - 10What drug is a stimulant laxative? What kind of drug is this?Bethanacol
Muscarinic agonist - 11What do muscarinic antagonists do? What are their effects on the pupils?Inhibit the PNS
Pupil dilation - 12What drug is used to treat sinus bradycardia? What type of drug is this?Atropine
Muscarinic antagonist - 13Both muscarinic antagonists and B2 agonists can treat what?Asthma, as they block PNS/increase SNS effects eg. bronchodilation
- 14What do Inhibitors of Acetylcholinesterase do? What does it do for the PNS?Prevent the breakdown of acetylcholine to increase neurotransmission
Increases PNS activity eg. secretions, SM tone, hypotension, bradycardia - 15Which drug reverses skeletal muscle relaxants? What type of drug is this?Neostigmine
AChE inhibitor - 16What inhibitor of AchE aids Alzheimers?Donepezil
- 17What are the 5 main types of drugs impacting cholinergic transmission?1. Skeletal muscle relaxants (cholinergic)
2. Ganglion blockers (cholinergic)
3. Muscarinic agonists
4. Muscarinic antagonists
5. Inhibitors of AchE
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- BMS03 - Nerve Signalling Flashcards on BMS03-1023 Pharmacology of Cholinergic Transmissions, created by Evian Chai on 22/04/2020.
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