Flashcards
Bacterial colonisation & Infection
Cards in this deck (14)
- 1Define: Colonisation.the presence of bacteria in/on a host with growth & proliferation without invasion.
- 2Define: Virulence.measure of the severity of the disease caused by an agent of infection.
- 3Name an infection with spreads directly (person-to-person).Mycobacterium tuberculosis
SARS-CoV-2 - 4Name an infection which spreads from vector to vertebrate.Plague
Yellow fever - 5Name an infection which spreads frmom a vertebrate.Rabies
Q fever - 6Name an infection spread from a vector.Malaria
- 7Suggest a pathogen located in the following areas: a) GI tract b) Vagina c) Skin d) Naso/Oropharnyxa) E. coli
b) E. coli
c) Staphylococcus aureus
d) Staphylococcus aureus - 8In what 3 ways can normal flora be protective?1. Non-specific stimulation of immune responses.
2. Competitive bacterial interference.
3. Niche occupation. - 9Suggest 3 factors which may promote colonisation.1. Pili
2. Fimbriae
3. Adhesins - 10What are pili & fimbriae?Long, thin protein polymers.
- 11Define: Invasiveness.ability of a pathogen to invade.
- 12Suggest 3 factors which ease invasion.1. Colonisation factors
2. Secreted factors that enable invasion into cells.
3. Evasion of immune system - 13Describe the invasion process of Gonococci.Gonococcus adheres to & invades columnar epithelium.
Replicates in basement membrane.
Invades into cells via disseminating from blood.
Induces an inflammatory response --> symptoms. - 14Describe the process of invasion of Streptococcus pneumoniae.Nasopharyngeal transmission.
Interacts with complement ==> impairs neutrophil recruitment (evading immune).
Mucus degradation.
Pili-mediated binding to host cell receptors.
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- University - Medicine FoM Year 1 (Microbiology) Flashcards on Bacterial colonisation & Infection, created by Jacob Coe on 15/01/2022.
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- Jacob Coe
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