Flashcards
Thymus & T Cell Creation
Cards in this deck (9)
- 1Thymus At PubertyIncreases in size
- 2Thymus by 30Decreased in size
- 3Site of T Cell CreationBone marrow
- 4Creation of TCRsDone during maturity in the thymus
- 5Splicing of TCR GenesDone randomly, so that each T cell ends up with a different TCR
- 6Pro's of Random TCR GenerationEnsures diversity, which is essential when detecting diverse Ags
- 7Cons of Random TCR GenerationMay not be functional- have to be screened
- 8Strongly Binding TCRsMay cause autoimmune disorders and are directly apoptosed in -ve selection
- 9Weakly Binding/Non Functional TCRsCannot bind and will die by neglect
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- Year 2 Flashcards on Thymus & T Cell Creation, created by gina_evans0312 on 16/04/2014.
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- gina_evans0312
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