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195797
Interstitial Lung Disease (reduced compliance, diffusion capacity and lung volume)
Description
Pathology Mind Map on Interstitial Lung Disease (reduced compliance, diffusion capacity and lung volume), created by Emma Jones on 07/09/2013.
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pathology
pathology
Mind Map by
Emma Jones
, updated more than 1 year ago
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Created by
Emma Jones
over 10 years ago
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Resource summary
Interstitial Lung Disease (reduced compliance, diffusion capacity and lung volume)
Fibrosing
UIP: Usual: unknown cause, temporally heterogeneous, honeycomb lung, expanded alveolar septa
NSIP: Non-specific: idiopathic, temporally homogeneous
COP: Cryptogenic organising pneumonia
Autoimmune related: RA, SLE
Pneumoconiosis: inhaled dusts: anthracosis, silicosis, asbetosis
Asbestosis: thick collagen layer on lung parenchyma, may calcify
Acute interstitial lung disease
ARDS: Acute Respiratory Distress Syndrome / DAD: Diffuse alveolar damage
MACRO: red heavy lungs
MICRO:
Oedema in alveolar walls
Hyaline membranes: fibrin + epithelial cell debris
Type II pneumocytes proliferate & differentiate to type I
Causes
Trauma, infection, shock, gastric aspiration, gas inhalation, DIC
Respiratory distress in the newborn = ARDS in newborn
Birthweight <2.5kg, <36wks gestation, maternal diabetes, caesarean
Insufficient surfactant
Alveoli collapse, hypoxia
Cell damage, oedema, fibrin
Hyaline membrane
Acute interstitial pneumonia = ARDS without known cause
Sarcoidosis
Systemic disease, disseminated well-formed granulomas
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