Interstitial Lung Disease (reduced compliance, diffusion capacity and lung volume)

Description

Pathology Mind Map on Interstitial Lung Disease (reduced compliance, diffusion capacity and lung volume), created by Emma Jones on 07/09/2013.
Emma Jones
Mind Map by Emma Jones, updated more than 1 year ago
Emma Jones
Created by Emma Jones over 10 years ago
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Resource summary

Interstitial Lung Disease (reduced compliance, diffusion capacity and lung volume)
  1. Fibrosing
    1. UIP: Usual: unknown cause, temporally heterogeneous, honeycomb lung, expanded alveolar septa
      1. NSIP: Non-specific: idiopathic, temporally homogeneous
        1. COP: Cryptogenic organising pneumonia
          1. Autoimmune related: RA, SLE
            1. Pneumoconiosis: inhaled dusts: anthracosis, silicosis, asbetosis
              1. Asbestosis: thick collagen layer on lung parenchyma, may calcify
            2. Acute interstitial lung disease
              1. ARDS: Acute Respiratory Distress Syndrome / DAD: Diffuse alveolar damage
                1. MACRO: red heavy lungs
                  1. MICRO:
                    1. Oedema in alveolar walls
                      1. Hyaline membranes: fibrin + epithelial cell debris
                        1. Type II pneumocytes proliferate & differentiate to type I
                        2. Causes
                          1. Trauma, infection, shock, gastric aspiration, gas inhalation, DIC
                        3. Respiratory distress in the newborn = ARDS in newborn
                          1. Birthweight <2.5kg, <36wks gestation, maternal diabetes, caesarean
                            1. Insufficient surfactant
                              1. Alveoli collapse, hypoxia
                                1. Cell damage, oedema, fibrin
                                  1. Hyaline membrane
                            2. Acute interstitial pneumonia = ARDS without known cause
                            3. Sarcoidosis
                              1. Systemic disease, disseminated well-formed granulomas
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