GIT Neoplasms

Emma Jones
Mind Map by , created about 6 years ago

Pathology Mind Map on GIT Neoplasms, created by Emma Jones on 09/08/2013.

Emma Jones
Created by Emma Jones about 6 years ago
patho. jars.. formative
Clinical Pathology (301-400) MCQs- Year 4 PMU
Med Student
Musculoskeletal Pathology
Suleman Shah
The Lymphatic System
james liew
General Pathoanatomy Final MCQs (301-400)- 3rd Year- PMU
Med Student
General Pathoanatomy Final MCQs (401-519)- 3rd Year- PMU
Med Student
General Pathoanatomy Final MCQs (201-300)- 3rd Year- PMU
Med Student
patho. practical slides
Pathology of Alimentary Tract 2 (Ruminant Forestomachs/ Glandular stomach)
GIT Neoplasms
1 Squamous cell carcinoma: raised edge with central ulceration or white plaque
1.1 Oesophagus
1.1.1 Alcohol, smoking, hot beverages, nutritional deficiency, HPV
1.1.2 Middle 1/3 of oesophagus, grey white plaque in masses or diffuse thicknening
1.1.3 Insidious onset, 5yr survival 9%
1.1.4 Dysphagia, odynophagia, obstruction, +/- ulceration
1.2 Oropharynx
1.3 Anus: HP infection, precursor = condyloma accuminatum
2 Adenoma
2.1 Pleomorphic adenoma of salivary gland
2.2 Oesophagus
2.3 Colon
2.3.1 Dysplasia: nuclear hyperchromasia, FAP
2.4 Appendix
3 Adenocarcinoma
3.1 Stomach
3.1.1 Clinical: dyspepsia, dysphagia, altered bowel habits, nausea, anaemia
3.1.2 Intestinal type: bulky & glandular, Signet ring cell type: diffuse
3.1.3 Antrum & lesser curvature
3.2 Duodenum
3.3 Colon
3.3.1 Tall columnar cells, variable differentiation & gland formation
3.3.2 Insidious development, IDA, occult bleeding, ab cramps, BM change
3.4 Appendix
3.4.1 Mucocele: benign cyst
3.4.2 Pseudomyoma peritoneii: slow tumour, mucus production> ascites
3.4.3 Obstruction + enlargement mimics acute appendicitis
4 Lymphoma
4.1 Stomach: lymphocytic infiltrate in lamina propria
4.1.1 Cause chronic inflammation: EBV & H.pylori infection
4.1.2 Dyspepsia, epigastric pain, spreads to lymph nodes
4.2 Small intestine: Coeliac disease
5 Gastrointestinal stromal tumour
5.1 Stomach
5.1.1 Well-circumscribed mass under mucosa +/- ulceration
5.1.2 Epitheloid or spindle cell
5.1.3 Asymptomatic, bleeding, mass effect
6 Carcinoid tumour
6.1 Small intestine
6.1.1 From endocrine cells, tan polypoid lesions, intramural or submucosal +/- ulceration, island & trabeculae cell structure
6.1.2 More common in ileum & jejunum
6.1.3 Asym, ab pain, metastatic disease, obstruction
6.1.4 Carcinoid syndrome: ileal tumours release vasoactive substances > flushing, sweating, bronchospasm, colicky ab pain, diarrhoea
6.2 Appendix
7 Non-neoplastic
7.1 Colon
7.1.1 Inflammatory polyp: injury + regeneration cycles
7.1.2 Hamartoma: growth of mature tissues at site where they normally develop, FAP
7.1.3 Hyperplastic polyps: decreased epith turnover in >70yo

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