255073
Description
Mind Map by Emma Jones, updated more than 1 year ago
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Created by Emma Jones
over 10 years ago
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Tubulointerstitial
diseases of the kidney
- Pyelonephritis
- Acute
pyelonephritis
- Obstructive
- Renal dysplasia, pregnancy
- Yellow ulcers in medulla,
red/oedematous pelvic mucosa, pus
- Polymorphic infiltrate,
abscesses, ulceration
of pelvis mucosa
- Renal dysplasia, pregnancy
- Non-obstructive
- Suppurative
- Staph aureus 2o
to osteomyelitis
- Enlarged, hyperaemic,
yellow, abscesses in cortex
- Staph aureus 2o
to osteomyelitis
- Suppurative
- Obstructive
- Necrotising papillitis
- Diabetes, analgesics
- Yellow/white friable
necrosis in papillae
- Pale infarcted papillae, haemorrhagic
border, polymorphic infiltrate
- Diabetes, analgesics
- Chronic pyelonephritis
- Analgesic nephropathy (phenacetin)
- Damage to vascular wall --> ischaemia
- Damage to vascular wall --> ischaemia
- Hypertension, proteinuria,
pyuria, haematura
- No bacteria found (usually)
- Atrophic/contracted, scars on
cortex, dilated pelvis/calyces,
sup & inf pole most affected
- Hyalinised glomeruli, periglomerular necrosis,
colloid casts in dilated tubules, interstital
fibrosis, lymphocytic infiltrate, arteriosclerosis
- Analgesic nephropathy (phenacetin)
- Xanthogranulomatous
nephritis
- Proteus species, mimics renal cell carcinoma
- Enlarged, yellow nodules
- Vacuolated cytoplasm (foam
cells), granulomas, giant
cells, micro-abscesses
- Proteus species, mimics renal cell carcinoma
- Renal tuburculosis
- 5% of active pulmonary TB
- Lesion in medulla --> caseous foci in
medulla and cortex --> destruction of kidney
- Caseating necrosis
- --> fibrosis/obstruction of
ureter, cystitis, epididymitis
- 5% of active pulmonary TB
- Acute
pyelonephritis
- Acute interstitial nephritis
- B-haem strep, diptheria,
leptospirosis, filariasis,
sulphonamides,
penicillin, methicillin
- Swollen, red/yellow,
dark red medulla
- Tubular epithelial
degeneration, haem and
bile casts in lumens,
inflammatory infiltrate
- B-haem strep, diptheria,
leptospirosis, filariasis,
sulphonamides,
penicillin, methicillin
- CMV
- Drug Induced acute: patchy
necrosis --> NSAIDs,
penicillin, sulphonamides
- Ischaemic acute tubular necrosis: sepsis,
shock, haemoglobulinuria, crush injury
- Cell necrosis, dilated
tubules, interstitial oedema
- Cell necrosis, dilated
tubules, interstitial oedema
- Myeloma kidney
- Pale, waxy, enlarged
- DCT blocked by eosinophilic Bence Jones protein
casts, amyloid in glomeruli, dystrophic calcification,
tubular epithelial cells with multiple nuclei
- Tubular damage & obstruction, nephrotic syndrome
- Pale, waxy, enlarged
- Toxic acute: antibiotics, heavy metals, organic solvents, cyclosporine A
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