PostMortem Changes

melian.yates
Mind Map by , created about 6 years ago

Doctorate Pathology Mind Map on PostMortem Changes, created by melian.yates on 10/18/2013.

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melian.yates
Created by melian.yates about 6 years ago
patho. jars.. formative
أطباء2020
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Pathology of Alimentary Tract 2 (Ruminant Forestomachs/ Glandular stomach)
melian.yates
PostMortem Changes
1 Blood and Congestion
1.1 Clotting
1.1.1 Be aware of postmortem clots; Can mistake for Thrombosis
1.1.1.1 Genuine Thrombus will be difficult to dislodge, and should have an obvious attachment to the vessel wall
1.2 Hypostatic Congestion
1.2.1 If an animal has been lying on one side after death, asymmetric congestion will result
1.2.1.1 Kidneys & Lungs
2 Pseudomelanosis
3 Biliary Imbibition
4 Autolysis
4.1 Tissue self-digestion due to release of intracellular lytic enzymes
4.1.1 Can resemble Necrosis
4.2 Tissues undergo autolysis at different rates
4.2.1 Rapid
4.2.1.1 Stomach, Intestines, Pancreas
4.2.2 Medium
4.2.2.1 Kidney
4.2.3 Slowly
4.2.3.1 Muscle, Skin
5 Putrefaction
5.1 Invasion of dead tissue by anaerobes ( Ex. Clostridia)
5.2 Tissue turns green/brown
5.2.1 Haemoglobin breakdown
5.2.2 Formation of Hydrogen Sulphide
5.2.2.1 Pseudomelanosis
5.3 Emphysema can occur in putrefied tissue if the organisms liberate gas
6 Agonal Changes
6.1 Occur around time of death (Irreversible circulatory failure)
6.2 Vascular congestion (Especially spleen)
6.2.1 Ex. Euthanasia w/ barbituates
6.3 Agonal regurgitation of GI contents
6.3.1 Lack of associated inflammation
6.4 Barbiturate crystal deposition in Endocardium
6.5 GIT Intussusception
6.5.1 1 piece of bowel telescopes inside another
7 Incidental Findings
7.1 Postmortem -> Surgical Biopsy
7.2 "Lesions" @ PME or Exploratory surgery
7.2.1 Mistakenly biopsied
7.2.2 Inappropriately assigned as significant
7.2.3 Inappropriately assigned as cause of death
7.3 Aging changes
7.3.1 Rigidity of bones, joints and connective tissue
7.3.2 "Wear & tear" to joints
7.3.3 Accumulation of metabolic products in cells
7.3.4 Splenic siderofibrosis
8 Lungs
8.1 Mineralization
8.2 Osseous metaplasia
8.2.1 gritty, hard bits
8.3 Anthracosis
8.3.1 Lungs contain fine 1 -2mm black foci in subpleural region
8.3.1.1 Where anthracotic pigment present
8.3.1.2 Medulla of regional lymph nodes may also be black
8.4 Pigmented bronchial lymph nodes
9 Vasculature
9.1 Arteriosclerosis
9.2 Atherosclerosis
9.2.1 Fatty plaques building up
9.2.1.1 Usually underlying metabolic disease
9.3 Vessel mineralization
9.4 Endocardial mineralization
10 Drug Associated Changes
10.1 Barbituates
10.1.1 Local Rxn
10.1.2 Barbituate crystals
10.1.3 Splenomegaly
10.2 Steroids
10.2.1 Vacuolar hepatopathy
10.2.1.1 Glycogen builds up in cells (Liver)