PostMortem Changes

Mind Map by , created about 6 years ago

Doctorate Pathology Mind Map on PostMortem Changes, created by melian.yates on 10/18/2013.

Created by melian.yates about 6 years ago
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Pathology of Alimentary Tract 2 (Ruminant Forestomachs/ Glandular stomach)
PostMortem Changes
1 Blood and Congestion
1.1 Clotting
1.1.1 Be aware of postmortem clots; Can mistake for Thrombosis Genuine Thrombus will be difficult to dislodge, and should have an obvious attachment to the vessel wall
1.2 Hypostatic Congestion
1.2.1 If an animal has been lying on one side after death, asymmetric congestion will result Kidneys & Lungs
2 Pseudomelanosis
3 Biliary Imbibition
4 Autolysis
4.1 Tissue self-digestion due to release of intracellular lytic enzymes
4.1.1 Can resemble Necrosis
4.2 Tissues undergo autolysis at different rates
4.2.1 Rapid Stomach, Intestines, Pancreas
4.2.2 Medium Kidney
4.2.3 Slowly Muscle, Skin
5 Putrefaction
5.1 Invasion of dead tissue by anaerobes ( Ex. Clostridia)
5.2 Tissue turns green/brown
5.2.1 Haemoglobin breakdown
5.2.2 Formation of Hydrogen Sulphide Pseudomelanosis
5.3 Emphysema can occur in putrefied tissue if the organisms liberate gas
6 Agonal Changes
6.1 Occur around time of death (Irreversible circulatory failure)
6.2 Vascular congestion (Especially spleen)
6.2.1 Ex. Euthanasia w/ barbituates
6.3 Agonal regurgitation of GI contents
6.3.1 Lack of associated inflammation
6.4 Barbiturate crystal deposition in Endocardium
6.5 GIT Intussusception
6.5.1 1 piece of bowel telescopes inside another
7 Incidental Findings
7.1 Postmortem -> Surgical Biopsy
7.2 "Lesions" @ PME or Exploratory surgery
7.2.1 Mistakenly biopsied
7.2.2 Inappropriately assigned as significant
7.2.3 Inappropriately assigned as cause of death
7.3 Aging changes
7.3.1 Rigidity of bones, joints and connective tissue
7.3.2 "Wear & tear" to joints
7.3.3 Accumulation of metabolic products in cells
7.3.4 Splenic siderofibrosis
8 Lungs
8.1 Mineralization
8.2 Osseous metaplasia
8.2.1 gritty, hard bits
8.3 Anthracosis
8.3.1 Lungs contain fine 1 -2mm black foci in subpleural region Where anthracotic pigment present Medulla of regional lymph nodes may also be black
8.4 Pigmented bronchial lymph nodes
9 Vasculature
9.1 Arteriosclerosis
9.2 Atherosclerosis
9.2.1 Fatty plaques building up Usually underlying metabolic disease
9.3 Vessel mineralization
9.4 Endocardial mineralization
10 Drug Associated Changes
10.1 Barbituates
10.1.1 Local Rxn
10.1.2 Barbituate crystals
10.1.3 Splenomegaly
10.2 Steroids
10.2.1 Vacuolar hepatopathy Glycogen builds up in cells (Liver)