Inflammation through tissue damage

Charlotte White0377
Mind Map by Charlotte White0377, updated more than 1 year ago
Charlotte White0377
Created by Charlotte White0377 about 6 years ago
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mind map of inflammation through tisue damage

Resource summary

Inflammation through tissue damage
  1. Endothelial Damage
    1. Activation of Hageman Factor (XII)
      1. Prekallikrein
        1. Kallikrein
          1. Kinninogen --> Bradykinin
            1. Increase in vascular permeability. Vasodilation. Pain. Smooth muscle contraction
        2. Activated clotting cascade
          1. Thrombin
            1. Fibrinopeptides and Fibrin Clot
            2. Activated fibrinolytic system
              1. Plasmin
                1. Fibrinopeptides and fibrin clot
                  1. Fibrin Degredation
                    1. Increase in vascular permeability. Neutrophil chemotaxis
                  2. Complement Activation
                    1. Anaphylatoxins C3a, C5a
                      1. Extravasion of monocytes and neutrophis to the site of complement activation
                        1. Mast Cell Degredation
                          1. Increase in vascular permeability. Smooth muscle contractions
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