Supplied by the renal arteries and goes into the inter lobar to arcuate artery and vein to undergo filtration.
It exits thru renal vein, while the filtrate exits thru the ureter.
1.1.1 Glomerulus View
1.2 Anatomy of Tubules
Consists of 2 types of nephrons:
Cortical 75% and juxtamedullary which is the other 25%.
2 Formation of Urine
Comes in 3 basic steps
2. Add, the efferent tubules actively secrete stuff across the cellular membrane
3. Reabsorption by the efferent tubules.
2.1 Types of Flitrations
A. Filtered but nor reabsorbed/secreted
B. Some of them is reabsorbed
C. All of them are reabsorbed.
D. All of them are filtered and secreted out.
3 Renal Blood Flow
Blood flow is 1200ml/min in males
20-25% of resting cardiac output.
Renal Plasma Flow = Renal blood flow (100 - Haemotocrit)/100
3.1 Pressure in vessels
Experiment done with rats, but the study is similar to humans
Cjanges in afferent or efferent arteriolar tone causes changes in renal blood flow.
Q = P/R
Hence if perfusion pressure is constant.
Constriction in arterioles will lead to fall in RBF
Dilation of arterioles will lead to rise in RBF
Changes with pressure to keep blood/fluid pressure constant.
it changes tone of arterioles.