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MO16 Redox
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Questions in this quiz (11)
1In drug formulation and in vivo there is usually an oxygen radical that is involved in or initiates oxidation.
- ATrue
- BFalse
2Choose the incorrect statement.
- AHeat and light accelerate free radical formation.
- BAfter the first radical forms it quickly reacts e.g. with the drug and new radicals form (propagation) until the reaction is terminated.
- CStoring drugs at cold temperatures slows free radical formation compared to room temperature storage.
3Cytochrome P450 enzyme pathways involve ROS (reactive oxygen species) as natural byproducts.
- ATrue
- BFalse
4Choose the incorrect statement.
- AAlkenes can be oxidised to epoxides.
- BAlkenes in ring systems can be oxidised to diols.
- CPolyunsaturated fatty acids used in formulations are prone to oxidative cleavage.
- DThiols can be oxidised to form disulfide bridges.
- EThioethers are prone to oxidation and form sulfones then sulfoxides.
5Which of these is not a group formed by aromatic ring oxidation?
- AEpoxide
- BKetone
- CPhenol
- DPhenyl
6What is often the reductant in organic chemistry?
- AHydride ion (H)
- BHydroxide ion (OH-)
7Drug instability in formulations and storage due to reduction of the drug is common.
- ATrue
- BFalse
8Which of these functional groups is NOT prone to reduction?
- AAldehydes
- BKetones
- CCarboxylic acids
- DAzos
- ENitros
- FDisulfides
- GPhenols
9Choose the incorrect statement about photolysis.
- AAromatic rings and conjugated systems are prone because they can absorb higher wavelengths of light
- BIt is exposure to electromagnetic radiation that may result in complex chemical reactions hence decompositions of drugs
- CIt involves free radical formation and oxidation
10Folic acid is an example of a drug that is prone to photodegradation.
- ATrue
- BFalse
11Drugs can degrade circulating in surface capillaries due to UV radiation.
- ATrue
- BFalse
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- PHCY211 (Molecules) Quiz on MO16 Redox, created by Mer Scott on 13/04/2018.
- Author
- Mer Scott
- Language
- English
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