VIRUS

VIRUS

1. ACELLULAR AGENTS

   • VIRUSES
     • Protein & nucleic acid
   • VIROIDS
     • Only RNA
   • SATELLITES
     • Only nucleic acids
   • PRIONS
     • Only proteins

2. Major cause of diseases

   • Important members of aquatic world
     • Important in evolution
       • Important model system in molecular biology

3. GENERAL PROPERTIES

   • VIRION
   • BACTERIOPHAGES
   • ARCHAEAL VIRUS
   • EUKARYOTIC VIRUS
   • CLASSIFIED INTO FAMILY
     • Genome structure
     • Life cycle
     • Morphology
     • Genetic relatedness

4. STRUCTURES

   • Capsids
     • Helical
     • Complex
     • Icosahedral
   • Envelopes
   • Enzyme
   • Viral genomes
   • Size range
     • ~10-400nm in diameter

5. VIRAL MUTIPLICATION

   • Steps
     • Attachment to host cells
       • Entry
         • Uncoating of genome
           • Synthesis
             • Assembly
               • Release

6. TYPES OF VIRAL INFECTIONS

   • Infections in bacteria and archaea
   • Infections in eukaryotic cells
   • Viruses and cancer

7. CULTIVATION AND ENUMERATION

   • Hosts for bacterial and archaeal viruses
   • Hosts for animal viruses
   • Hosts for plant viruses
   • Quantification of viruses
   • Measuring concentration of infectious units
   • Measuring biological effects