Antidepressants

Antidepressants

1. Drugs associated with serotonin syndrome

   • SSRIs
   • SNRIs
   • MAOIs
   • St. John's Wort
   • Kava Kava
   • Tryptophan
   • Cocaine
   • Amphetamines

2. Serotonin syndrome

   • Mental status changes
   • Autonomic instability
   • Neuromuscular abnormalities
   • Treatment
     • Benzodiazepines
     • Cyproheptadine

3. TCA overdose

   • Convulsions
   • Coma
   • Cardiotoxicity
   • Hyperpyrexia
   • Confusion and hallucination