Notes
Definitions
Content of the notes (3)
Page 1
Lecture 1
Paracelsus (1493–1541) Poison is in everything
Is defined as what the body does to the drug (ADME processes)
ADME processes occur simultaneously
Significance of PK
Dose and Rate
Individualizing Therapy
Dosage adjustment for drugs
How food affects
optimize compliance
Math
Page 2
Lecture 2
Ln (N) = 2.303 Log (N)
To linearize it, we convert the concentration (y-axis) to logarithm scale while the time (x-axis) remains as is– called semilog scale
Zero Order - line; constant slope
First Order - log