Flashcards
Motor Proteins- Myosin
Cards in this deck (37)
- 1Duty RatioHow often the protein is in use
- 2ProcessiveFollow distinct steps in order- no randomness
- 3No of Myosin typesApprox 40
- 4Size of Myosin family core120kDa
- 5Myosin SuperfamilyG-protein (same as kinesin)
- 6Myosin 2Muscle Myosin
- 7Myosin V- Direction of movementFrom minus end to plus end
- 8Heavy/Light chains in Myosin V2 heavy, multiple light chains
- 9Myosin V- Role of IQ motifsTo bend lever arm- keeps lever arm rigid & allows regulation
- 10Myosin V-No of IQ motifs6
- 11Myosin V-N-terminus MotorGlobular myosin motor ATPase
- 12Myosin V-Coiled coil neckLinks cargo binding domain to lever arms
- 13Myosin V-Lever ArmContains 6 IQ motifs & 6 light chains
- 14Myosin V- Light chain 8Part of cargo binding domain
- 15Myosin V- Converter DomainWhere ATP cycle causes changes
- 16Myosin V- Changes in converter domain are amplified by theLever arm
- 17—Movement of steps- same method for measurement as kinesin
- 18Myosin V- Length moved by each head72nm
- 19Myosin V- Length moved by cargo36 nm
- 20Myosin V- Change in angle of motor arms (pre/post stroke)70 degrees
- 21Myosin V- Removal of one protein headCauses failure of protein to work
- 22Myosin V- Movement ModelHand over Hand
- 23Myosin V- Duty RatioHigh
- 24Myosin V- Monomer?Dimer
- 25Myosin IV- Direction of MovementFrom plus end to minus end
- 26Myosin IV- No of IQ motifs2
- 27Myosin IV- Chains2 Heavy, multiple light
- 28Myosin IV- Lever arm extensionAttached to actin binding heads with binding site for light chains of proximal tail
- 29Myosin IV- N-terminalGlobular motor with special insert domain
- 30Myosin IV- Proximal tailForms lever arm extension made of light chains and binds it to medial tail
- 31Myosin IV- Medial tailCoiled coil connecting lever arm extension to distail tail
- 32Myosin IV- Distail tailConnects medial tail and cargo binding domain
- 33Myosin IV- C-terminusDistal tail & cargo binding domains
- 34Myosin IV- No of bound light chainsSame as Myosin II
- 35Myosin IV- Step size36nm
- 36Myosin IV- Role of light chainsNo of light chains involved regulates level of movement
More = more movement - 37Myosin IV- Adding InsertCauses light chain binding region to move in opposite direction to Myosin V
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- Structural Basis for Biological Function (Molecular Motors) Flashcards on Motor Proteins- Myosin, created by gina_evans0312 on 15/12/2013.
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