Flashcards
BMS10-1017 - Blood Cells: RBC WBC and platelets
Cards in this deck (20)
- 1What is the size and shape of a red blood cell?7 uM
Biconcave disc - 2RBCs can only undergo anaerobic metabolism of glucose becauseThey have no organelles
- 3...diffrentiates to.... after ejecting ...., which then becomes a RBC after....Normocyte-->Reticulocyte after nucleus ejected
Organelles lost - 4What do platelets (thrombocytes) look like and what do they do? What are they from and where?1. Biconcave dark granules
They play a role in haematostasis /maintaining blood vessels by forming clots
2. Formed from fragmentation of macrophages in bone marrow - 5What are the precursors of platelets and what do they look like? What fuses together to become vesicles that form platelets?1. Macrophages
Giant cells with a single irregular nucleus
3. Endoplasmic reticulum tubules - 6Eosinophils, Basophils and Neutrophils are what kind of leukocyte?Granulocytes (multi lobed)
- 7Monocytes and Lymphocytes are what kind of leukocyte?Agranulocytes (one nuclues, no lobes)
- 8Which leukocyte has many lobes, makes up 90% of the granulocytes, release granules for phagocytic activity, and die after a single burst of activity?Neutrophils
- 9Which leukocyte is bi-lobed, stains blue, and releases inflammatory histamine?Basophil
- 10Which leukocyte is bi-lobed, stains pink, releases antihistaminases in response to allergy/infection, and is phagocytic?Eosinophil
- 11Which leukocyte is largest, has a horse shoe shaped nuclues, presents antigens, and does phagocytosis?Monocytes
- 12What is the relationship between monocytes and macrophages?Monocytes become macrophages after leaving circulation
- 13Which leukocyte stains purple, has a single large round nucleus, and primarily provides specific immunity? What are the three types?Lymphocytes
1. T cells flag
2. B cells release antibodies
3. Natural Killer cells - 14At 2-2.5 weeks in utero, where are RBCs?Outside embryo in extraembryonic membrane as blood islands
- 15At 5 weeks, where do the blood islands migrate to?The liver, to start producing RBC and WBC
- 16Where do RBC/WBC production move to 5 months in utero?Bone marrow, but can migrate to liver/spleen if needed
- 17What is plasma? What is it made of?1. Fluid component of blood
2. Aqueous composition of salts, nutrients, plasma protein - 18What are the three plasma proteins?1. Albumin (transporters)
2. Fibrinogen (fibrin precursor)
3. Globulins (immunoglubulin-->antibodies) - 19Which cells have a lymphoid progenitor instead of myeoid?Small lymphocytes (B/T)
Large lymphocytes (Natural killer) - 20Summary
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- Description
- Review of blood cell types: erythrocytes, lymphocytes, granulocytes, monocytes and platelets. Plasma as the fluid matrix of the formed elements of blood. Describe the different types of blood cells, their origin, lifespan and functions Briefly consider plasma as the fluid matrix of blood
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- Evian Chai
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