AQA GCSE Biology B1.1.2 How our bodies defend themselves against infectious diseases

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Made from gcse biology specification 4401
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Question Answer
What are microorganisms that cause infectious disease are called? Pathogens
What are three types of microorganisms? Bacteria Virus Fungi
How do bacteria and viruses make us feel ill? Reproduce rapidly inside the body Produce poisons (toxins)
What microorganism damages the cells in which it reproduces? Viruses
How do white blood cells help to defend against pathogens? ■ingesting pathogens ■ producing antibodies ■ producing antitoxins
How do viruses cause disease? 1) Infect a body cell, get inside it and reproduce 2)Reproduces so many copies of itself that the cell burst open and is damaged 3)This takes place in many cells
How does ingesting pathogens work? 1) White blood cell detects a problem and moves towards the pathogen 2) engulfs a pathogen 3)white blood cell releases enzymes from are pathogen has been engulfed 4) pathogen digested over s period of minutes and is made harmless
How do antibodies protect the body against? 1)Antibodies attach onto antigens 2)Destroys pathogens
How do antitoxins destroy toxins? They deactivate toxins and make them safe
What leads to the immunity from a specific pathogen? The immune system of the body producing specific antibodies to kill that particular pathogen
What can stimulate antibody production in some cases? Dead or inactivated pathogens
What happens if a large proportion of the population is immune to a pathogen? The spread of the pathogen is very much reduced
What did Semmelweis recognize? The importance of hand-washing in the prevention of spreading some infectious diseases
What did Semmelweis insist doctors do? wash their hands before examining patients
What did Semmelweis find when doctors washer their hands? The number of deaths from infectious diseases in his hospital was greatly decreased
What do some medicines including paracetamol do? Help to relieve the symptoms of infectious disease, but do not kill the pathogens.
What do medicines such as Antibiotics, including penicillin do to pathogens? help to cure bacterial disease by killing infectious bacteria inside the body
What can Antibiotics not kill? Viral pathogens
Why cant antibiotics kill viral pathogens? As viral pathogens live and reproduce inside cells
What does the use of antibiotics greatly reduce the number of deaths from infectious bacterial diseases
What does overuse and inappropriate use of antibiotics result in? An increase in the rate of development of antibiotic resistant strains of bacteria.
How have strains of bacteria, including MRSA, developed resistance? By natural selection
How can further resistance to antibiotics be prevented? By avoiding over-use of antibiotics
What do mutations of new pathogens produce? New strains
What happens if antibiotics and vaccinations are no longer effective against a new resistant strain of the pathogen? The new strain will then spread rapidly because people are not immune to it and there is no effective treatment
What do antibiotics kill? individual pathogens of the non-resistant strain
What happens when individual resistant pathogens survive and reproduce? the population of the resistant strain increases
Why aren't antibiotics not used to treat non-serious infections, such as mild throat infections? so that the rate of development of resistant strains is slowed down
What does the development of antibiotic-resistant strains of bacteria necessitate? the development of new antibiotics
How can people be immunised against a disease by introducing small quantities of dead or inactive forms of the pathogen into the body called a vaccination
What do vaccines do? stimulate the white blood cells to produce antibodies that destroy the pathogens
What is the purpose of vaccines? To makes a person immune to future infections by the microorganism
Why is a person immune to future infections by the microorganism after a vaccine? As The body can respond by rapidly making the correct antibody, in the same way as if the person had previously had the disease.
What is the MMR vaccine used for? to protect children against measles, mumps and rubella
What is required for investigating the action of disinfectants and antibiotics Uncontaminated cultures of microorganisms
Why is the petri dish and culture media sterilised? Petri dishes and culture media must be sterilisedbefore use to kill unwanted microorganisms
Why is the innoculated loop sterilised? inoculating loops used to transfer microorganisms to the media must be sterilised by passing them through a flame
Why is the lid of the petri dish sterilised? the lid of the Petri dish should be secured with adhesive tape to prevent microorganisms from the air contaminating the culture.
What is the maximum cultures are incubated at in schools and colleges? 25 degrees centigrade
Why is a temperature of 25 degrees centigrade used to incubate the culture? as it greatly reduces the likelihood of growth of pathogens that might be harmful to humans.
What temperature is used in industry to incubate cultures? A higher temperature of about 37 is used to produce more rapid growth
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