Type III Secretion System

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Flashcards by gina_evans0312, updated more than 1 year ago
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Description

Medical Microbiology (Protein Secretion) Flashcards on Type III Secretion System, created by gina_evans0312 on 03/06/2014.

Resource summary

Question Answer
Gram Bacteria Found In Gram -ve
No of proteins 20
Purpose Channels effector proteins to orchestrate specific response
Structure Outer membrane ring, inner rod, inner membrane ring, FscF multimer 'needle'
Secretion System Required to Make TIIISS SecY-inner rod and needle are made by secretion through the base
Exs A before Activation Requires contact with a host protein -ExsA is bound to ExsD, keeping it inactive
ExsA On Host Cell Contact ExsA is released, and binds to ExsE
ExsE Released by cell contact on ExsC
Chaperone Protein Unique for each protein to be pumped & must be removed since folded proteins can't pass through the T3SS
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