Flashcards
Training and Glycaemic Control
Cards in this deck (7)
- 1Give reasons for increased glucose uptake into the skeletal muscles post exercise.Increased perfusion to the muscles, increased GLUT 4 translocation, Increase glycogen synthase (more glucose stores as glycogen), increased production of GLUT 4.
- 2What happens over a short period and longer period to our glycemic control as we uptake exercise? What effect does this have on our chances of getting type II diabetes?Short term it peaks the falls, over the long term we see elevated levels of glycemic control, decreasing our chances of getting type II diabetes.
- 3Give an example of a drug which will decrease your chance of getting type II diabetes. How does the use of this drug compare to a healthy lifestyle?Medormin, not as effective as improving lifestyle.
- 4Give reasons why training would increase your glycemic control.Capillarization so more blood flow to muscles. Increased insulin receptors on myocytes. Increased GLUT 4. Increased glycogen synthase activity.
- 5Describe the mechanism which reduces the amount of eNOS as a result of elevated lipids or TNF alpha in the cell.Lipids and TNF cause serine to become phosphorylated instead of tyrosine on the insulin receptor. This means less IRS-1 is phosphorylated, so less IP3 Kinase is created which leads to less eNOS being created.
- 6Give some of the positive effects of AMPK.Amplified insulin sensitivity, switches on PCG1 alpha to increase mitochondria production, TBC1D4 levels increased so more GLUT 4 translocation and increases GLUT 4 synthesis
- 7In what group of people would we find the higher intramuscular lipid content? Explain why even though the two groups one is positive and the other a negative.Type II diabetics, then trained people. Type II diabetics have high lipids in cells which inhibits the action of GLUT 4 translocation where as trained people have high lipids but they are surrounded by mitochondria and are therefore regularly broken down as fuel then replaced.
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- Exercise Metabolism Flashcards on Training and Glycaemic Control, created by alexlpeart on 01/05/2013.
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